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CHO/mDEC205

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (17) AAK1 (1) ADC Antibody (3) ADC Linker (2) ADC Payload (1) Adenosine Receptor (19) Adenylate Cyclase (3) Adrenergic Receptor (23) Akt (2) Amino Acid Decarboxylase (1) Amylin Receptor (1) Amyloid-β (5) Anaplastic lymphoma kinase (ALK) (1) Androgen Receptor (3) Angiotensin Receptor (1) ANGPTL (2) Antibiotic (1) Antifolate (2) Apelin Receptor (APJ) (1) Apoptosis (45) Aquaporin (1) ATP-binding cassette (ABC) transporters (1) Autophagy (4) Bacterial (8) Bcl-2 Family (3) Beta-lactamase (1) Beta-secretase (3) Biochemical Assay Reagents (39) Bradykinin Receptor (2) c-Fms (1) c-Kit (1) c-Met/HGFR (1) C-type Lectin-like Receptors (CTLRs) (3) Cadherin (5) Calcium Channel (5) CaMK (1) Cannabinoid Receptor (6) Casein Kinase (2) Caspase (32) Cathepsin (3) CCR (10) CD19 (3) CD20 (1) CD22 (1) CD276/B7-H3 (1) CD28 (1) CD3 (2) CD47 (1) CD73 (1) CGRP Receptor (2) Chloride Channel (1) Claudin (1) Complement System (3) COX (16) CRAC Channel (1) CRFR (3) CTLA-4 (1) CXCR (10) Cyclin G-associated Kinase (GAK) (1) Cytochrome P450 (4) Discoidin Domain Receptor (1) DNA/RNA Synthesis (9) Dopamine Receptor (8) Drug Derivative (3) Drug Intermediate (2) Drug Metabolite (11) Drug-Linker Conjugates for ADC (1) Dynamin (1) E3 Ligase Ligand-Linker Conjugates (10) Early 2 Factor (E2F) (1) EGFR (13) Emopamil Binding Protein (1) Endogenous Metabolite (22) Endothelin Receptor (5) Environmental Pollutants (3) Ephrin Receptor (1) Epigenetic Reader Domain (1) ERK (6) Estrogen Receptor/ERR (2) Eukaryotic Initiation Factor (eIF) (2) FAAH (1) Factor VIII (1) Fc Receptor (FcR) (3) Ferroportin (2) FGFR (6) FKBP (2) FLT3 (1) Fluorescent Dye (2) Formyl Peptide Receptor (FPR) (1) Free Fatty Acid Receptor (5) FXR (1) G protein-coupled Bile Acid Receptor 1 (11) G Protein-coupled Receptor Kinase (GRK) (1) G2A (GPR132) (1) GABA Receptor (9) Gap Junction Protein (1) GCGR (6) GHSR (2) GLP Receptor (7) GLUT (1) Glycosidase (1) GlyT (1) GPR35 (1) GPR6 (1) GPR84 (1) GPR88 (1) GSK-3 (1) Guanylate Cyclase (2) HBV (1) HCV (3) Hepcidin (1) Herbicide (2) Histamine Receptor (1) Histone Acetyltransferase (1) Histone Methyltransferase (2) HIV (1) HSP (1) Human leukocyte immunoglobulin (Ig)-like receptors (LILR) (1) IFNAR (1) iGluR (10) Influenza Virus (2) Insulin Receptor (1) Integrin (10) Interleukin Related (29) IRE1 (1) Isotope-Labeled Compounds (17) Kallikrein (1) Kisspeptin Receptor (1) KMO (1) LDLR (3) Leukotriene Receptor (1) Ligands for E3 Ligase (1) Liposome (10) Lipoxygenase (1) LPL Receptor (8) LXR (1) mAChR (11) MCHR1 (GPR24) (2) Melanocortin Receptor (3) Melanopsin Receptor (1) Melatonin Receptor (8) Mesothelin (1) mGluR (8) MHC (1) Microtubule/Tubulin (2) Mitogen- and Stress-Activated Protein Kinase (MSK) (2) MMP (1) Motilin Receptor (1) mTOR (2) Myosin (1) Na+/Ca2+ Exchanger (1) NAMPT (1) Natriuretic Peptide Receptor (NPR) (1) Neurokinin Receptor (8) Neuropeptide FF Receptor (1) Neuropeptide Y Receptor (5) Neurotensin Receptor (4) NF-κB (9) NOD-like Receptor (NLR) (1) Notch (3) Nucleoside Antimetabolite/Analog (4) OGT (2) Opioid Receptor (25) Orexin Receptor (OX Receptor) (9) Orphan GPCR (3) Oxytocin Receptor (1) P-glycoprotein (1) P2Y Receptor (1) p38 MAPK (7) PACAP Receptor (2) PAI-1 (1) Parasite (2) PARP (8) PCSK9 (3) PD-1/PD-L1 (8) PDGFR (2) PERK (1) Phosphatase (2) Phosphodiesterase (PDE) (1) Phospholipase (1) Phosphorylase (1) PI3K (3) PI4K (1) PKA (8) Potassium Channel (6) PPAR (1) Prolyl Endopeptidase (PREP) (1) Prostaglandin Receptor (5) PROTAC Linkers (14) PROTACs (2) Proteasome (7) Protein Prenyltransferase (1) Pyroptosis (1) Radionuclide-Drug Conjugates (RDCs) (1) Ras (1) Reactive Oxygen Species (ROS) (1) Reference Standards (36) RET (1) RIP kinase (1) ROR (1) SARS-CoV (6) Scavenger Receptor Class B type I (SR-BI） (1) Ser/Thr Protease (7) Serotonin Transporter (2) SGLT (2) Sigma Receptor (2) Smo (1) Sodium Channel (10) Sodium Phosphate Cotransporter (1) Somatostatin Receptor (4) Src (1) Steroid Sulfatase (1) TGF-beta/Smad (4) TGF-β Receptor (4) Thrombin (2) TNF Receptor (14) Toll-like Receptor (TLR) (2) Topoisomerase (2) Transmembrane Glycoprotein (28) Trk Receptor (4) TRP Channel (9) Tyrosinase (3) ULK (1) Urotensin Receptor (4) Vasopressin Receptor (1) VEGFR (11) Wnt (3) β-catenin (2) γ-secretase (3)
By Research Areas:	Cancer (167) Cardiovascular Disease (39) Endocrinology (39) Infection (25) Inflammation/Immunology (407) Metabolic Disease (54) Neurological Disease (180)
Click Chemistry:	PROTAC Synthesis (1) Azide (3) Alkynes (1)
Oligonucleotides:	Adenosine (1) Pegylated Lipids (7) Nucleoside Analogs (1) Polymers (5) Cholesterol (3)

726

Inhibitors & Agonists

Fluorescent Dyes

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Peptides

MCE Kits

379

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Natural
Products

167

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Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

GMP Molecules

Targets Recommended: Choline Kinase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-128140

Z-FY-CHO 5+ Cited Publications Z-Phe-Tyr-CHO	Cathepsin	Neurological Disease Metabolic Disease
Z-FY-CHO (Z-Phe-Tyr-CHO) is a potent and specific cathepsin L (CTSL) inhibitor .

HY-P1001

Ac-DEVD-CHO Maximum Cited Publications 46 Publications Verification	Caspase	Cancer
Ac-DEVD-CHO is a Caspase-3 inhibitor with a K_i value of 230 pM.

HY-W588725A

*N3-Cho* bromide** 1 Publications Verification Azido-CHOline bromide	Biochemical Assay Reagents	Others
N3-Cho (Azido-choline) bromide is a click chemistry reagent containing an azide group that can be used in the synthesis of cell membrane structures .

HY-P10149

Ac-IEPD-CHO 1 Publications Verification	Caspase	Cancer
Ac-IEPD-CHO is a reversible granzyme B inhibitor with a K_i of 80 nM . Ac-IEPD-CHO is also a caspase-8 inhibitor .

HY-120019

Ac-YVAD-CHO L-709049	Interleukin Related Apoptosis Caspase	Inflammation/Immunology
Ac-YVAD-CHO (L-709049) is a potent, reversible, specific tetrapeptide interleukin-lβ converting enzyme (ICE) inhibitor with mouse and human K_i values of 3.0 and 0.76 nM. Ac-YVAD-CHO is also a caspase-1 inhibitor. Ac-YVAD-CHO can suppress the production of mature IL-lβ .

HY-136727

Ac-LEVD-CHO 1 Publications Verification	Caspase	Cancer
Ac-LEVD-CHO is a caspase-4 inhibitor. Ac-LEVD-CHO is a peptide with the sequence of Ac-Leu-Glu-Val-Asp-al .

HY-113963

Ac-IETD-CHO	Apoptosis	Cancer
Ac- IETD- CHO is a potent, reversible inhibitor of granzyme B and caspase-8. Ac- IETD- CHO inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failure. Ac- IETD- CHO also inhibits cytotoxic T lymphocytes induced cell death .

HY-120234

Z-LLNle-CHO Z-Leu-Leu-Nle-CHO; GSII	γ-secretase Proteasome Apoptosis	Cancer
Z-LLNle-CHO (Z-Leu-Leu-Nle-CHO) is a γ-secretase inhibitor I. Z-LLNle-CHO induces caspase and ROS-dependent apoptosis by blocking the Akt-mediated pro-survival pathway. Z-LLNle-CHO can be used in cancer research, such as breast cancer and leukaemia .

HY-108312A

*Ac-VEID-CHO* TFA**	Caspase	Neurological Disease
Ac-VEID-CHO (TFA) is a peptide-derived caspase inhibitor and has potency of inhibition for Caspase-6, Caspase-3 and Caspase-7 with IC₅₀ values of 16.2 nM, 13.6 nM and 162.1 nM, respectively. Ac-VEID-CHO (TFA) can be used for the research of neurodegenerative conditions including Alzheimer’s and Huntington’s disease .

HY-49390

(S)-Glutarimide-amide-Py-piperidine-CHO	E3 Ligase Ligand-Linker Conjugates	Cancer
(S)-Glutarimide-amide-Py-piperidine-CHO is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

HY-134454

Z-Pro-Pro-CHO	Prolyl Endopeptidase (PREP) Parasite	Infection
Z-Pro-Pro-CHO is a potent inhibitor of prolyl oligopeptidase (POP), with extremely high affinity for human prolyl oligopeptidase (HsPOP) (IC₅₀=0.012 μM), and it also effectively inhibits the activity of Schistosoma mansoni prolyl oligopeptidase (SmPOP) (IC₅₀=0.16 μM). Z-Pro-Pro-CHO does not block the phosphorylation of ERK or the production of TNF-α or IFN-γ in immune cells from presensitized mice, nor does it induce harmful phenotypes in cultured Schistosoma mansoni schistosomula. Z-Pro-Pro-CHO only partially inhibits epithelial cell wound healing at extremely high concentrations. Z-Pro-Pro-CHO finds wide application in studies related to schistosomiasis .

HY-176509A

DSPE-PEG2000-CHO	Liposome	Others
DSPE-PEG2000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG2000-CHO can be used for drug delivery .

HY-138408

BocNH-PEG4-CH2CHO	PROTAC Linkers	Cancer
BocNH-PEG4-CH2CHO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-137392

Cathepsin L-IN-4 1-Naphthalenesulfonyl-Ile-Trp-CHO	Cathepsin	Others
Cathepsin L-IN-4 is an inhibitor of cathepsin L with IC₅₀ at nanomolar concentrations .

HY-P4222

IETD-CHO Caspase-8-IN-1	Caspase	Others
IETD-CHO (Caspase-8-IN-1) is a potent caspase-8 inhibitor .

HY-161795

SP3CHO	Drug Metabolite	Cancer
SP3CHO is an active metabolite generated by the metabolism of SP3N in cell culture by the action of amine oxidase. SP3CHO can induce polyubiquitination of specific proteins by recruiting the SCFFBXO22 E3 ligase complex. SP3CHO can be used in cancer therapy research .

HY-176509C

DSPE-PEG5000-CHO	Liposome	Others
DSPE-PEG5000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG5000-CHO can be used for drug delivery .

HY-176509

DSPE-PEG1000-CHO	Liposome	Others
DSPE-PEG1000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG1000-CHO can be used for drug delivery .

HY-W035376

m-PEG6-CH2CH2CHO	ADC Linker PROTAC Linkers	Cancer
m-PEG6-CH2CH2CHO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG6-CH2CH2CHO is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-P10241

Ac-LEHD-CHO	Apoptosis Caspase	Cancer
Ac-LEHD-CHO is an inhibitor for caspase 8/9. Ac-LEHD-CHO prevents GalN/TNF-α-induced hepatotoxicity and hepatocyte apoptosis .

HY-P5830A

*Biotin-DEVD-CHO* TFA**	Caspase Orexin Receptor (OX Receptor)	Others
Biotin-DEVD-CHO (TFA) is a biotin-conjugated form of the caspase-3 and -7 inhibitor – Ac-DEVD-CHO. Biotin-DEVD-CHO (TFA) can be used for affinity purification of the active caspase-3, -6, -7, and -8. Biotin-DEVD-CHO (TFA) can detect the active caspase-3 in vitro .

HY-P5890A

*YVAD-CHO* TFA**	Caspase Interleukin Related	Neurological Disease Inflammation/Immunology
YVAD-CHO TFA is an interleukin-1β converting enzyme (ICE, caspase 1) inhibitor (K_i: 0.76 nM). YVAD-CHO TFA inhibits mature IL-1β production. YVAD-CHO TFA partially delays motoneurone death in lesioned facial nerve mice .

HY-P5830

Biotin-DEVD-CHO	Caspase	Others
Biotin-DEVD-CHO can be used for affinity labeling of Caspase-8 following in vitro caspase cleavage .

HY-P5890

YVAD-CHO	Interleukin Related Caspase	Neurological Disease Inflammation/Immunology
YVAD-CHO is an interleukin-1β converting enzyme (ICE, caspase 1) inhibitor (K_i: 0.76 nM). YVAD-CHO inhibits mature IL-1β production. YVAD-CHO partially delays motoneurone death in lesioned facial nerve mice .

HY-108312

Ac-VEID-CHO	Caspase	Neurological Disease
Ac-VEID-CHO is a peptide-derived caspase inhibitor and has potency of inhibition for Caspase-6, Caspase-3 and Caspase-7 with IC₅₀ values of 16.2 nM, 13.6 nM and 162.1 nM, respectively. Ac-VEID-CHO also inhibits VEIDase activity an IC₅₀ value of 0.49 µM. Ac-VEID-CHO can be used for the research of neurodegenerative conditions including Alzheimer’s and Huntington’s disease .

HY-120019A

*Ac-YVAD-CHO* acetate** L-709049 acetate	Interleukin Related Caspase Apoptosis	Inflammation/Immunology
Ac-YVAD-CHO (L-709049) acetate is a potent, reversible, specific tetrapeptide interleukin-lβ converting enzyme (ICE) inhibitor with mouse and human K_i values of 3.0 and 0.76 nM. Ac-YVAD-CHO acetate is also a caspase-1 inhibitor. Ac-YVAD-CHO acetate can suppress the production of mature IL-lβ .

HY-155921

mPEG5000-CHO mPEG5000-Aldehyde	Biochemical Assay Reagents	Others
mPEG5000-CHO participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.

HY-W1115221

Desamino lenalidomide-azetidine-CHO	E3 Ligase Ligand-Linker Conjugates	Cancer
Desamino lenalidomide-azetidine-CHO is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

HY-W011254

Ac-VAD-CHO Ac-Val-Ala-Asp-CHO	Caspase	Cancer
Ac-VAD-CHO (Ac-Val-Ala-Asp-CHO) is a pan-caspase inhibitor. Ac-VAD-CHO inhibits dissipation of MMP and cytochrome c release in hypoxia-exposed cells .

HY-P5936

Ac-AAVALLPAVLLALLAP-DEVD-CHO DEVD-CHO-CPP 32	Caspase	Cancer
Ac-AAVALLPAVLLALLAP-DEVD-CHO (DEVD-CHO-CPP 32) is a potent and reversible caspase-3 inhibitor .

HY-138096

Z-LLF-CHO Z-Leu-Leu-Phe-CHO	Proteasome	Cancer
Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) is a potent inhibitor of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex (K_i = 460 nM). Z-LLF-CHO is also a NF-κB nuclear translocation inhibitor .

HY-P10146

Ac-LETD-CHO	Caspase	Cancer
Ac-LETD-CHO is a caspases 8 inhibitor. Ac-LETD-CHO has specific inhibition to casp-8 with an IC₅₀ value of 6.71 nM. Ac-LETD-CHO can be used for the research of anticancer .

HY-P2374

Ac-DMQD-CHO	Caspase Apoptosis	Neurological Disease
Ac-DMQD-CHO is a selective inhibitor for caspase 3, with IC₅₀ of 39 nM. Ac-DMQD-CHO reduces apoptosis, and exhibits neuroprotective efficacy .

HY-136733

Ac-DNLD-CHO Ac-Asp-Asn-Leu-Asp-CHO	Caspase	Infection Neurological Disease
Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is a Caspase-3/7 inhibitor (IC₅₀: 9.89, 245 nM respectively; K_i ^app: 0.68, 55.7 nM respectively). Ac-DNLD-CHO can be used for research of caspase-mediated apoptosis diseases, such as neurodegenerative disorders and viral infection diseases .

HY-P10955

*Ac-AAVALLPAVLLALLAPVAD-CHO* TFA**	Caspase	Others
Ac-AAVALLPAVLLALLAPVAD-CHO (TFA) is a composite of Ac-VAD-CHO. Ac-AAVALLPAVLLALLAPVAD-CHO (TFA) is a non-selective caspase inhibitor as well as a cell permeable hydrophobic sequence derived from K-FGF .

HY-P3234

Ac-ESMD-CHO	Casein Kinase	Others
Ac-ESMD-CHO is an inhibitor of caspase-3 and caspase-7. Ac-ESMD-CHO inhibits proteolytic cleavage of the caspase-3 precursor peptide (CPP32) at the Glu-Ser-Met-Asp (ESMD) site .

HY-134567

Ac-VDVAD-CHO	Caspase	Others
Ac-VDVAD-CHO is a caspase-2/3 inhibitor (IC₅₀: 46 and 15 nM) .

HY-P10007

Z-Gly-Pro-Phe-Leu-CHO Z-GPFL-CHO	Proteasome	Cancer
Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde that acts as a highly selective and potent proteasomal inhibitor (K_i = 1.5 µM for branched chain amino acid preferring, 2.3 µM for small neutral amino acid preferring, and 40.5 µM for chymotrypsin-like activities; IC₅₀ = 3.1 µM for peptidyl-glutamyl peptide hydrolyzing activity) .

HY-P5956

Ac-AAVALLPAVLLALLAP-LEHD-CHO	Caspase	Cancer
Ac-AAVALLPAVLLALLAP-LEHD-CHO is an inhibitor of caspases 4, 5 and 9. Ac-AAVALLPAVLLALLAP-LEHD-CHO shows protective effects upon Neocarzinostatin (HY-111183)-treated MCF-7 cells .

HY-P5834

Boc-AEVD-CHO	Caspase Apoptosis	Inflammation/Immunology
Boc-AEVD-CHO is a Caspase 8 inhibitor useful in the study of apoptosis and immune and inflammatory diseases .

HY-136727A

*Ac-LEVD-CHO* TFA**	Caspase Apoptosis	Cancer
Ac-LEVD-CHO (TFA) is an inhibitor of caspase-4. Ac-LEVD-CHO (TFA) can inhibit the expression and secretion of IL-1α expression as well as the activation of caspase-4 induced by the T. denticola periodontal pathogen surface protein Td92 in human gingival fibroblasts. Ac-LEVD-CHO (TFA) can also reduce the apoptosis due to the expression of the dominant negative adenoviral RNA-dependent protein kinase in A549 and PC3 cancer cell lines .

HY-134567A

*Ac-VDVAD-CHO* TFA**	Caspase	Others
Ac-VDVAD-CHO (TFA) is a caspase-2/3 inhibitor (IC₅₀: 46 and 15 nM) .

HY-P5955

Ac-AAVALLPAVLLALLAP-LEVD-CHO	Caspase	Cancer
Ac-AAVALLPAVLLALLAP-LEVD-CHO is a cell-permeable caspase-4 inhibitor that has antitumor activity .

HY-P5938

Ac-AAVALLPAVLLALLAP-YVAD-CHO	Caspase	Cancer
Ac-AAVALLPAVLLALLAP-YVAD-CHO is a cell-permeable caspase-1 inhibitor that has antitumor activity .

HY-138383

**CHO-C-PEG2-C-CHO**	PROTAC Linkers	Cancer
CHO-C-PEG2-C-CHO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-134703

Acid-PEG12-CHO	PROTAC Linkers	Cancer
Acid-PEG12-CHO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-134702

Mal-PEG12-CHO	PROTAC Linkers	Cancer
Mal-PEG12-CHO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-138912

Cho-Arg TFA	Liposome	Others
Cho-Arg TFA is a steroid-based cationic lipid with an L-Arginine headgroup. Cho-Arg TFA shows a remarkably high optimized plasmid DNA transfection efficacy .

HY-158709

Cho-es-Lys	Biochemical Assay Reagents Liposome	Others
Cho-es-Lys is a cationic lipid synthesized by coupling natural cholesterol and amino acids, which has high gene transfection efficiency. Cho-es-Lys can be used in drug delivery research .

HY-176509D

DSPE-PEG10000-CHO	Liposome	Others
DSPE-PEG10000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG10000-CHO can be used for drug delivery .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0169

Hyodeoxycholic acid 5+ Cited Publications HDCA	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Steroids Source Classification	G protein-coupled Bile Acid Receptor 1 Endogenous Metabolite
Hyodeoxycholic acid is a secondary bile acid formed in the small intestine by the gut flora, and acts as a TGR5 (GPCR19) agonist, with an EC₅₀ of 31.6 µM in CHO cells.

HY-128853

Taurodeoxycholate sodium 5+ Cited Publications	Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids Source Classification	Endogenous Metabolite G protein-coupled Bile Acid Receptor 1 PARP Apoptosis NF-κB PKA
Taurodeoxycholate sodium salt is a bile salt-related anionic detergent. Taurodeoxycholate sodium salt is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholate sodium salt is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) exhibits anti-inflammatory and neuroprotective effects .

HY-B1899

Taurodeoxycholic acid 5+ Cited Publications TaurodeoxyCHOlate	Structural Classification Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite G protein-coupled Bile Acid Receptor 1 PARP Apoptosis NF-κB PKA
Taurodeoxycholate sodium salt is a bile salt-related anionic detergent. Taurodeoxycholic acid is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholic acid is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholic acid (TDCA) exhibits anti-inflammatory and neuroprotective effects .

HY-B1180

Vinburnine 3 Publications Verification (-)-Eburnamonine; (-)-Vincamone	Apocynaceae Cardiovascular Disease Alkaloids Classification of Application Fields Hunteria zeylanica Plants Disease Research Fields Indole Alkaloids Source Classification	Drug Metabolite mAChR
Vincamone is a vinca alkaloid and a metabolite of vincamine, is a vasodilator.

HY-17038

Agomelatine Maximum Cited Publications 9 Publications Verification S-20098	Alkaloids Neurological Disease Classification of Application Fields Other Alkaloids Endogenous metabolite Disease Research Fields Source Classification	Melatonin Receptor 5-HT Receptor Endogenous Metabolite
Agomelatine (S-20098) is a specific agonist of MT1 and MT2 receptors with K_is of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively . Agomelatine is a selective 5-HT2C receptor antagonist with pK_is of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively .

HY-W089835

Sodium taurodeoxycholate hydrate 1 Publications Verification	Structural Classification Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Steroids Source Classification	G protein-coupled Bile Acid Receptor 1 Endogenous Metabolite PARP Apoptosis NF-κB PKA
Sodium taurodeoxycholate hydrate is a bile salt-related anionic detergent. Sodium taurodeoxycholate hydrate is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Sodium taurodeoxycholate hydrate is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate-d₆ (TDCA) exhibits anti-inflammatory and neuroprotective effects .

HY-W017113

2-Mercaptobenzothiazole 1 Publications Verification	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Endogenous Metabolite
2-Mercaptobenzothiazole is an activator of the aryl hydrocarbon receptor (AhR) , inhibiting thyroid hormone synthesis and dopamine beta-hydroxylase activity . 2-Mercaptobenzothiazole promotes bladder cancer cell invasion by altering the conformation of the AhR ligand binding domain (LBD), activating AhR transcription, and upregulating the mRNA and protein expression of target genes CYP1A1 and CYP1B1 . 2-Mercaptobenzothiazole inhibits thyroid peroxidase (TPO) with an IC₅₀ value of 11.5 μM, induces histological changes such as follicular cell hypertrophy in Xenopus laevis tadpoles, delaying metamorphosis . 2-Mercaptobenzothiazole increases chromosomal aberrations and sister chromatid exchanges (SCEs) in Chinese hamster ovary (CHO) cells, and enhances carcinogenicity in F344/N rats . 2-Mercaptobenzothiazole inhibits norepinephrine synthesis in mice and completely blocks the conversion of exogenous dopamine to norepinephrine in rat cardiomyocytes .

HY-113291

5'-Deoxyadenosine 2 Publications Verification	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Nucleoside Antimetabolite/Analog Phosphorylase
5'-Deoxyadenosine is a 5'-methylthioadenosine phosphorylase substrate and deoxyadenosine. 5'-Deoxyadenosine serves as a non-metabolizable substrate for nucleoside transport assays only in cells lacking 5'-methylthioadenosine phosphorylase .

HY-N0169R

Hyodeoxycholic acid (Standard) HDCA (Standard)	Structural Classification Human Gut Microbiota Metabolites Endogenous metabolite Steroids Source Classification	Reference Standards Endogenous Metabolite G protein-coupled Bile Acid Receptor 1
Hyodeoxycholic acid (Standard) is the analytical standard of Hyodeoxycholic acid. This product is intended for research and analytical applications. Hyodeoxycholic acid is a secondary bile acid formed in the small intestine by the gut flora, and acts as a TGR5 (GPCR19) agonist, with an EC50 of 31.6 µM in CHO cells.

HY-B1899R

Taurodeoxycholic acid (Standard) TaurodeoxyCHOlate (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite G protein-coupled Bile Acid Receptor 1 PARP Apoptosis NF-κB PKA
Taurodeoxycholic acid (Standard) is the analytical standard of Taurodeoxycholic acid. This product is intended for research and analytical applications. Taurodeoxycholate sodium salt is a bile salt-related anionic detergent. Taurodeoxycholic acid is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholic acid is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholic acid (TDCA) exhibits anti-inflammatory and neuroprotective effects[1][2][3][9][10].

HY-17038A

Agomelatine hydrochloride Maximum Cited Publications 9 Publications Verification S-20098 hydrochloride	Alkaloids Neurological Disease Classification of Application Fields Other Alkaloids Endogenous metabolite Disease Research Fields Source Classification	Melatonin Receptor 5-HT Receptor Endogenous Metabolite
Agomelatine hydrochloride (S-20098 hydrochloride) is a specific agonist of MT1 and MT2 receptors with K_is of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively . Agomelatine hydrochloride is a selective 5-HT2C receptor antagonist with pK_is of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively .

HY-17038B

Agomelatine (L(+)-Tartaric acid) Maximum Cited Publications 9 Publications Verification S-20098 L(+)-Tartaric acid	Alkaloids Neurological Disease Classification of Application Fields Other Alkaloids Endogenous metabolite Disease Research Fields Source Classification	Melatonin Receptor 5-HT Receptor Endogenous Metabolite
Agomelatine L(+)-Tartaric acid (S-20098 L(+)-Tartaric acid) is a specific agonist of MT1 and MT2 receptors with K_is of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively . Agomelatine L(+)-Tartaric acid is a selective 5-HT2C receptor antagonist with pK_is of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively .

HY-17038R

Agomelatine (Standard) S-20098 (Standard)	Structural Classification Alkaloids Other Alkaloids Endogenous metabolite Source Classification	Reference Standards Melatonin Receptor 5-HT Receptor Endogenous Metabolite
Agomelatine (Standard) is the analytical standard of Agomelatine. This product is intended for research and analytical applications. Agomelatine (S-20098) is a specific agonist of MT1 and MT2 receptors with K_is of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively . Agomelatine is a selective 5-HT2C receptor antagonist with pK_is of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively .

HY-123091

Ivangustin	Classification of Application Fields Terpenoids Sesquiterpenes Plants Compositae Disease Research Fields Piptanthus nepalensis (Hook.) D. Don Source Classification Cancer	Others
Ivangustin is a sesquiterpene isolated from the flower heads of the medicinal plant Inula britannica .

HY-134615

Mead ethanolamide	Alkaloids Neurological Disease Classification of Application Fields Other Alkaloids Endogenous metabolite Disease Research Fields Source Classification	Cannabinoid Receptor Endogenous Metabolite
Mead ethanolamide is an endogenous cannabinoid receptor agonist with K_d values of 753 nM and 1810 nM against CB1 and CB2, respectively .

HY-17038AR

Agomelatine hydrochloride (Standard) S-20098 hydrochloride (Standard)	Structural Classification Alkaloids Other Alkaloids Endogenous metabolite Source Classification	Melatonin Receptor 5-HT Receptor Endogenous Metabolite Reference Standards
Agomelatine (hydrochloride) (Standard) is the analytical standard of Agomelatine (hydrochloride). This product is intended for research and analytical applications. Agomelatine hydrochloride (S-20098 hydrochloride) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively . Agomelatine hydrochloride is a selective 5-HT2C receptor antagonist with pKis of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively .

HY-128853R

Taurodeoxycholate sodium salt (Standard)	Endogenous metabolite Steroids Source Classification	Reference Standards Endogenous Metabolite G protein-coupled Bile Acid Receptor 1 PARP Apoptosis NF-κB PKA
Taurodeoxycholate sodium salt (Standard) is a bile salt (Standard)-related anionic detergent. Taurodeoxycholate sodium salt (Standard) is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholate sodium salt (Standard) is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) exhibits anti-inflammatory and neuroprotective effects .

HY-N8497

Leoidin	Monophenols Microorganisms Phenols Source Classification	Bacterial
Leoidin is an OATP1B1 and OATP1B3 inhibitor with K_i values of 0.08 and 1.84 μM，respectively. Leoidin inhibits sodium fluorescein uptake in CHO cells expressing the human OATP1B1 and OATP1B3. Leoidin is an antibacterial agent against both Gram-positive and Gram-negative pathogens. Leoidin inhibits phenylalanyl-tRNA synthetase (PheRS) (IC₅₀= 42 μM) and inhibits protein synthesis in bacterial. Leoidin can be isolated from L. gangaleoides .

HY-113513

5-HEPE	Microorganisms Source Classification	Others
5(S)-HEPE is an active metabolite of eicosapentaenoic acid. It is formed from EPA by 5-lipoxygenase (5-LO). 5(S)-HEPE is an agonist of G protein-coupled receptor 119 (GPR119). It increases cAMP accumulation in CHO-K1 cells expressing human GPR119 when used at a concentration of 10 μM. 5(S)-HEPE increases glucose-induced insulin secretion from MING6 insulinoma pancreatic islets and glucagon-like peptide 1 (GLP-1) secretion from HuTu 80 adenocarcinoma cells when used at a concentration of 10 μM. Serum levels of 5(S)-HEPE are elevated in patients with hyperlipidemia.

HY-N17875

Demethylsalvicanol (+)-Demethylsalvicanol	Structural Classification Labiatae Phenols Polyphenols Plants Pueraria montana (Lour.) Merr. Source Classification	Drug Derivative
Demethylsalvicanol ((+)-Demethylsalvicanol), a diterpene, is a anticancer agent with an IC₅₀ of 0.71 μg/mL against P388 murine leukemia cells. Demethylsalvicanol induces cytotoxic activity against leukemia cells and insect Sf9 cells. Demethylsalvicanol acts as an antifeedant against Leptinotarsa decemlineata. Demethylsalvicanol can be used for the research of leukemia .

HY-N15339A

Convolamine hydrochloride	Structural Classification Alkaloids Microorganisms Tropane Alkaloids Source Classification	Sigma Receptor
Convolamine hydrochloride is a tropane alkaloid and a potent Sigma-1 receptor positive allosteric modulator with an IC₅₀ value of 289 nM. Convolamine hydrochloride can be extracted from Convolvulus plauricalis. Convolamine hydrochloride exhibits cognitive-improving and neuroprotective properties. Convolamine hydrochloride can be used in research related to Wolfram syndrome and Alzheimer's disease .

Cat. No.	Product Name	Chemical Structure

HY-15036S

Diclofenac-d4
Diclofenac-d₄ is the deuterium labeled Diclofenac. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

HY-15036S1

Diclofenac-13C6
Diclofenac- ¹³C₆ is the ¹³C₆ labeled Diclofenac. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.

HY-135119

Salmeterol-d3
Salmeterol-d₃ is a deuterium labeled Salmeterol. Salmeterol is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC₅₀s of 9.6, 6.1, and 5.9, respectively .

HY-15037S2

Diclofenac-13C6 sodium

Diclofenac- ¹³C₆ (Sodium) is the ¹³C₆ labeled Diclofenac (Sodium). Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.

HY-15037S1

Diclofenac-d4 sodium

Diclofenac-d₄ (sodium) is the deuterium labeled Diclofenac sodium. Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

HY-B0188S

Mianserin-d3

Mianserin-d3 is the deuterium labeled Mianserin (HY-B0188). Mianserin (Mianserine) is an orally active H1 receptor antagonist. Mianserin can activate κ-opioid receptor and octopamine receptor. Mianserin increases ERK1/2 and CREB phosphorylation, and antagonizes full κ-opioid agonist and Dynorphin A (HY-P1333)-induced MAPK phosphorylation. Mianserin modulates social and exploratory behaviour, raises electroconvulsive thresholds. Mianserin can be used for the research of neurological disease, such as depression and epilepsy .

HY-17038S2

Agomelatine-d3
Agomelatine-d₃ is the deuterium labeled Agomelatine. Agomelatine (S-20098) is a specific agonist of MT1 and MT2 receptors with K_is of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively . Agomelatine is a selective 5-HT2C receptor antagonist with pKis of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively .

HY-12789S

Etrasimod-d9
Etrasimod-d₉ (APD334-d₉) is a deuterium labeled Etrasimod (HY-12789). Etrasimod (APD334) is a potent, selective and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor with an IC₅₀ value of 1.88 nM in CHO cells. .

HY-128853S

Taurodeoxycholate-d6 sodium

Taurodeoxycholate-d₆ sodium salt is a bile salt-related anionic detergent. Taurodeoxycholate-d₆ sodium salt is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholate-d₆ sodium salt is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate-d₆ (TDCA) exhibits anti-inflammatory and neuroprotective effects .

HY-14397S

Indomethacin-d4
Indomethacin-d₄ (Indometacin-d₄) is a deuterium labeled Indomethacin. Indomethacin is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2, with IC₅₀s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells . Indomethacin disrupts autophagic flux by disturbing the normal functioning of lysosomes .

HY-N0169S

Hyodeoxycholic acid-d5
Hyodeoxycholic acid-d₅ is the deuterium labeled Hyodeoxycholic acid. Hyodeoxycholic acid is a secondary bile acid formed in the small intestine by the gut flora, and acts as a TGR5 (GPCR19) agonist, with an EC50 of 31.6 µM in CHO cells.

HY-17038S1

Agomelatine-d4
Agomelatine-d₄ is the deuterium labeled Agomelatine. Agomelatine (S-20098) is a specific agonist of MT1 and MT2 receptors with K_is of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively . Agomelatine is a selective 5-HT2C receptor antagonist with pKis of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively .

HY-14397S1

Indomethacin-d4 Methyl Ester
Indomethacin-d₄ Methyl Ester is the deuterium labeled Indomethacin. Indomethacin (Indometacin) is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2, with IC₅₀s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells . Indomethacin disrupts autophagic flux by disturbing the normal functioning of lysosomes .

HY-14773S

(Rac)-Mirabegron-d5
(Rac)-Mirabegron-d₅ is a deuterium labeled (Rac)-Mirabegron. (Rac)-Mirabegron is the racemate of Mirabegron. Mirabegron is a selective β3-adrenoceptor agonist .

HY-124104S

Aldicarb sulfoxide-d3
Aldicarb sulfoxide-d₃ is the deuterium labled Aldicarb sulfoxide (HY-124104). Aldicarb sulfoxide is a metabolite of Aldicarb. Aldicarb sulfoxide affects the glutathione-linked enzymes in CHO-K1 cells. Aldicarb sulfoxide inhibits cholinesterase (ChE) and carboxylesterase (CaE) with IC₅₀ of 10 μM for both in zebrafish .

HY-14302S1

Salmeterol-d5
Salmeterol-d5 is a deuterated labeled Salmeterol . Salmeterol (GR33343X) is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC₅₀s of 9.6, 6.1, and 5.9, respectively .

HY-17453S

Salmeterol-d3 xinafoate
Salmeterol-d₃ (xinafoate) is the deuterium labeled Salmeterol xinafoate. Salmeterol (GR 33343X) xinafoate is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC₅₀s of 9.6, 6.1, and 5.9, respectively .

HY-17453S1

Salmeterol-13C6 xinafoate
Salmeterol- ¹³C₆ (xinafoate) is the ¹³C₆ labeled Salmeterol (xinafoate). Salmeterol (GR 33343X) xinafoate is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively.

HY-15037S

Diclofenac-13C6 sodium heminonahydrate

Diclofenac- ¹³C₆ (sodium heminonahydrate) is the ¹³C-labeled Diclofenac Sodium. Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

HY-W753345

2,6-Dichlorodiphenylamine-13C6

2,6-Dichlorodiphenylamine- ¹³C₆ (2,6-Dichloro-N-phenylaniline- ¹³C₆) is the ¹³C-labeled 2,6-Dichlorodiphenylamine (HY-W012126). 2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium (HY-15037) and has anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a?COX?inhibitor, with?IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells.

HY-108235AS1

Lanicemine-d5 dihydrochloride
Lanicemine-d₅ dihydrochloride (AZd₆765-d₅ dihydrochloride) is the deuterium labeled Lanicemine dihydrochloride (HY-108235A). Lanicemine (AZD6765) dihydrochloride is a low-trapping NMDA channel blocker (K_i of 0.56-2.1 μM for NMDA receptor; IC₅₀s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects .

HY-108235S1

(R)-Lanicemine-d5
(R)-Lanicemine-d₅ ((R)-AZd₆765-d₅) is the deuterium labeled (R)-Lanicemine (HY-108235C). (R)-Lanicemine ((R)-AZD6765) is the less active R-enantiomer of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (K_i of 0.56-2.1?μM for NMDA receptor; IC₅₀s of 4-7?μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects.

Targets Recommended: Choline Kinase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-18964G

MG-101 Calpain inhibitor I; Ac-LLnL-CHO; ALLN	Proteasome Apoptosis	Cancer
MG-101 (GMP) (Calpain inhibitor I (GMP)) is MG-101 (HY-18964) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with K_is of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer .

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