1 Result for "

COX-2-IN-51

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "COX-2-IN-51" in MCE Product Catalog:

Cat. No.: HY-170585
CAS No.: 3064260-49-4
Target:  

COX NF-κB

Research Areas:  

Inflammation/Immunology

COX-2-IN-51 (E25) is a potent COX-2 inhibitor, with an IC50 of 70.7 nM. COX-2-IN-51 significantly inhibits LPS-induced release of NO and PGE2, expression of COX-2 and iNOS, and activation of NF-κB pathway. COX-2-IN-51 exhibits anti-inflammatory and analgesic effects in diverse murine models through inhibiting NF-κB pathway. COX-2-IN-51 has lower gastrointestinal side effects than Indomethacin (HY-14397) .
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