1 Result for "

CXCR4 antagonist 5

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CXCR4 antagonist 5" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-146372
CAS No.: 2304749-86-6
Target:  

CXCR

Research Areas:  

Cancer

CXCR4 antagonist 5 (compound 23) is a highly potent CXCR4 antagonist with an IC50 value of 8.8 nM. CXCR4 antagonist 5 can inhibit CXCL12-induced cytosolic calcium increase (IC50 = 0.02 nM) and inhibits CXCR4/CXLC12-mediated chemotaxis. CXCR4 antagonist 5 has good physicochemical properties and in vitro safety profiles, inhibiting CYP isozymes and hERG marginally or moderately .
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