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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
120 Results for "
CaLL
" in MedChemExpress (MCE) Product Catalog:
Products (120)
120 Results for "CaLL" in MCE Product Catalog:
20
20 Publications Verification
Synonyms: CI-1011; PD-148515
Target:
Research Areas:
Avasimibe (CI-1011; PD-148515) is an orally active acyl coenzyme A-cholesterol acyltransferase (ACAT; also called SOAT)) inhibitor with IC50s of 24 and 9.2 µM for ACAT1 and ACAT2, respectively . Avasimibe can be used for the research of prostate cancer .
15
Category:
Anti-aging Endocrine diseases Amino acids Endogenous metabolite Microorganisms Disease markers Nervous System Disorder Disease Research Fields Cardiovascular System Disorder Cancer
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9
9 Cited Publications
Cat. No.: HY-P3160
CAS No.: 86088-83-7
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This product is a human Fibronectin obtained by recombinant expression in a rice expression system.
7
7 Cited Publications
Research Areas:
BCATc Inhibitor 2 is a selective branched-chain aminotransferase (BCAT) inhibitor for research of neurodegenerative diseases. The IC50s of 0.2 μM, 0.8 μM and 3.0 μM for rat cytosolic isoenzyme rBCATc, human cytosolic isoenzyme hBCATc and rat mitochondrial isoenzyme rBCATm, respectively. BCATc, also called BCAT1, is in the cytoplasm .
3
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Miglitol (BAY-m1099) is an orally active antidiabetic compound that inhibits the breakdown of glycoconjugates into glucose. Miglitol inhibits glycoside hydrolase enzymes called α-glucosidases. Miglitol inhibits oxidative stress-induced apoptosis and mitochondrial ROS over-production in endothelial cells by enhancement of AMP-activated protein kinase. Dietary supplementation with Miglitol from pre-onset stage in OLETF rats delays the onset and development of diabetes and preserves the insulin secretory function of pancreatic islets .
3
3 Cited Publications
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HS38 is a potent, selective, and ATP-competitive inhibitor of death-associated protein kinase 1 (DAPK1) and zipper-interacting protein kinase (ZIPK, also called DAPK3), with Kds of 300 nM and 280 nM, respectively. HS38 is also a PIM3 inhibitor with an IC50 of 200 nM. HS38 can be used for the research of smooth muscle related disorders .
2
2
2 Cited Publications
Cat. No.: HY-N5056
CAS No.: 13190-34-6
Category:
Cruciferous vegetables Natural Products Other Diseases Plants Brassicaceae Disease Research Fields
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2
2 Cited Publications
Cat. No.: HY-N0650S8
CAS No.: 105591-10-4
Synonyms: (-)-Serine-d3; (S)-Serine-d3
1
1 Cited Publications
Cat. No.: HY-P2671
CAS No.: 39024-57-2
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1
1 Cited Publications
Cat. No.: HY-N0650S
CAS No.: 201595-68-8
Synonyms: (-)-Serine-13C3; (S)-Serine-13C3
1
1
1 Cited Publications
Cat. No.: HY-139606
CAS No.: 2630950-38-6
VCP/p97 inhibitor-1 is a potent inhibitor of VCP/p97 (also called Cdc48, CDC-. 48, or Ter94) with an IC50 of 54.7 nM. VCP/p97 inhibitor-1 causes the dysregulation of protein homeostasis and disturbs the degradation of misfolded polypeptides by the ubiquitin-proteasome system (UPS) .
1
Category:
Triterpenes other families Terpenoids Plants Disease Research Fields Inflammation/Immunology
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1
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Indazole, also called isoindazole, a heterocyclic aromatic organic compound. Its derivatives display a broad variety of biological activities including anti-inflammatory, antibacterial, anti-HIV, antiarrhythmic, antifungal and antitumour properties. Indazole and its derivatives can be used for research of cancer, neurological disorders, cardiovascular diseases, gastrointestinal diseases .
Cat. No.: HY-N0650S11
CAS No.: 935275-35-7
Synonyms: (-)-Serine-d7; (S)-Serine-d7
Cat. No.: HY-147330B
Purity: 97.66%
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
SJ1008030 (compound 8) formic is a JAK2 PROTAC which selectively degrades JAK2. SJ1008030 formic inhibits MHH–CALL-4 cell growth with an IC50 of 5.4 nM. SJ1008030 formic can be used for the research of leukemia .
Synonyms: 2'-AMP; Adenosine 2'-phosphate; AMP 2'-phosphate
Cat. No.: HY-W011238
CAS No.: 6110-53-8
Synonyms: (Z)-1-Bromooctadec-9-ene
Target:
Research Areas:
Oleyl bromide ((Z)-1-Bromooctadec-9-ene) is a hydrophobic compound that can carry out ring-opening reaction through a process called "encapsulation". Oleyl bromine can also be used as the starting material in the synthesis of oleylphosphonates.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
