1. Metabolic Enzyme/Protease
  2. Dipeptidyl Peptidase
  3. Saikogenin A

Saikogenin A 

Cat. No.: HY-N6584 Purity: 98.31%
Handling Instructions

Saikogenin A, extracted from a Chinese herbal plant called Tsai-Fu, is a dipeptidyl peptidase-IV (DPP-IV) inhibitor.

For research use only. We do not sell to patients.

Saikogenin A Chemical Structure

Saikogenin A Chemical Structure

CAS No. : 5092-09-1

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Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Saikogenin A, extracted from a Chinese herbal plant called Tsai-Fu, is a dipeptidyl peptidase-IV (DPP-IV) inhibitor.

IC50 & Target


In Vitro

Saikogenin A has certain inhibitory effect on the enzyme DPP-IV. At a concentration of 20 μg/mL DPP-IV inhibition is 47.6%. DPP-IV is a non-classical serine aminopeptidase from its amino terminus of polypeptides and proteins (N-terminus) removing Xaa-Pro dipeptide[1].

In Vivo

Saikogenin A, an anti-inflammatory drug, is present in the crude extract of a Chinese herbal plant called Tsai-Fu. Saikogenin A is less effective in adrenalectomized rats than in normal rats in reducing the carrageenin-induced edema. The anti-inflammatory action of Saikogenin A are due to an increase in corticosterone caused by the release of arenocorticotropic hormone (ACTH) and a direct effect on the process of inflammation[2].

Molecular Weight







Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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Saikogenin ADipeptidyl PeptidaseDPPInhibitorinhibitorinhibit

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