1. Metabolic Enzyme/Protease
  2. Dipeptidyl Peptidase

Saikogenin A 

Cat. No.: HY-N6584 Purity: 98.31%
Handling Instructions

Saikogenin A, extracted from a Chinese herbal plant called Tsai-Fu, is a dipeptidyl peptidase-IV (DPP-IV) inhibitor.

For research use only. We do not sell to patients.

Saikogenin A Chemical Structure

Saikogenin A Chemical Structure

CAS No. : 5092-09-1

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5 mg USD 790 In-stock
Estimated Time of Arrival: December 31
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Description

Saikogenin A, extracted from a Chinese herbal plant called Tsai-Fu, is a dipeptidyl peptidase-IV (DPP-IV) inhibitor.

IC50 & Target

DPP-IV[1]

In Vitro

Saikogenin A has certain inhibitory effect on the enzyme DPP-IV. At a concentration of 20 μg/mL DPP-IV inhibition is 47.6%. DPP-IV is a non-classical serine aminopeptidase from its amino terminus of polypeptides and proteins (N-terminus) removing Xaa-Pro dipeptide[1].

In Vivo

Saikogenin A, an anti-inflammatory drug, is present in the crude extract of a Chinese herbal plant called Tsai-Fu. Saikogenin A is less effective in adrenalectomized rats than in normal rats in reducing the carrageenin-induced edema. The anti-inflammatory action of Saikogenin A are due to an increase in corticosterone caused by the release of arenocorticotropic hormone (ACTH) and a direct effect on the process of inflammation[2].

References
Molecular Weight

472.70

Formula

C₃₀H₄₈O₄

CAS No.

5092-09-1

SMILES
Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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Saikogenin A
Cat. No.:
HY-N6584
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Saikogenin A

Cat. No.: HY-N6584