406191-34-2
Chemical Structure
BCATc Inhibitor 2
- CAS No.: 406191-34-2
- Formula:C16H10ClF3N2O4S
- Molecular Weight:418.77
IUPAC Name: N'-(5-chlorobenzofuran-2-carbonyl)-2-(trifluoromethyl)benzenesulfonohydrazide
InChIKey: ZLQBZYKAQQWOTK-UHFFFAOYSA-N
SMILES: ClC1=CC=C2C(C=C(O2)C(NNS(C3=C(C=CC=C3)C(F)(F)F)(=O)=O)=O)=C1
Biological Activity: BCATc Inhibitor 2 is a selective branched-chain aminotransferase (BCAT) inhibitor for research of neurodegenerative diseases. The IC50s of 0.2 μM, 0.8 μM and 3.0 μM for rat cytosolic isoenzyme rBCATc, human cytosolic isoenzyme hBCATc and rat mitochondrial isoenzyme rBCATm, respectively. BCATc, also called BCAT1, is in the cytoplasm[1].
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BCATc Inhibitor 2 | 99.28% | BCATc Inhibitor 2 is a selective branched-chain aminotransferase (BCAT) inhibitor for research of neurodegenerative diseases. The IC50s of 0.2 μM, 0.8 μM and 3.0 μM for rat cytosolic isoenzyme rBCATc, human cytosolic isoenzyme hBCATc and rat mitochondrial isoenzyme rBCATm, respectively. BCATc, also called BCAT1, is in the cytoplasm. | ||||||||||||||||||||
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Keywords
