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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
Cathepsin B Substrate
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "Cathepsin B Substrate" in MCE Product Catalog:
2
2 Cited Publications
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Cat. No.: HY-162874
CAS No.: 3035557-60-6
diABZI-V/C-DBCO is a STING agonist with an EC50 of 1.47 nM. diABZI-V/C-DBCO activates the STING pathway, induces the production of IFN-I, and stimulates the secretion of IFN-β. diABZI-V/C-DBCO serves as a substrate for cathepsin B, and releases active diABZI-amine via cathepsin B-mediated cleavage. In an orthotopic mouse model of breast cancer, diABZI-V/C-DBCO increases serum IFN-β levels and the frequency of granzyme B + CD8 + T cells. diABZI-V/C-DBCO is applicable to research related to triple-negative breast cancer .
Synonyms: Arginine 4-methyl-7-coumarylamide hydrochloride
Cat. No.: HY-164278
CAS No.: 3035557-55-9
diABZI-V/C-Mal is a STING agonist (with a STING EC50 of 314 nM in TH1 dual reporter cells) and a Cathepsin B substrate. diABZI-V/C-Mal activates STING, thereby triggering the IRF3 signaling pathway. diABZI-V/C-Mal is cleaved by Cathepsin B to regenerate diABZI-NH2 .
Cat. No.: HY-P4500
CAS No.: 122630-71-1
Cat. No.: HY-155667A
Purity: 99.58%
Z-Nle-Lys-Arg-AMC acetate is a fluorogenic peptide substrate that specifically monitors cathepsin B activity over a broad pH range .
Cat. No.: HY-P2498A
Cat. No.: HY-158307
CAS No.: 2237216-27-0
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Phe-Lys(Trt)-PAB is a cathepsin B substrate, and a cleavable ADC linker. Phe-Lys(Trt)-PAB acts as a lysosomally cleavable substrate for cysteine protease cathepsin B, with cleavage enabling linked anticancer drug release via self-immolative spacer . Phe-Lys(Trt)-PAB can be used for synthesis of ADCs .
Cat. No.: HY-D1523
CAS No.: 100900-19-4
Cat. No.: HY-P2498
CAS No.: 839730-93-7
Cat. No.: HY-P4428
CAS No.: 141223-71-4
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Cat. No.: HY-155667
CAS No.: 1135364-14-5
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Z-Nle-Lys-Arg-AMC is a fluorogenic peptide substrate that specifically monitors cathepsin B activity over a broad pH range .
Cat. No.: HY-P11325
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Cat. No.: HY-118959A
CAS No.: 38789-84-3
Synonyms: Bz-Phe-Val-Arg-pNA hydrochloride
S2160 hydrochloride is a substrate of Cathepsin B that can be utilized in the calorimetric assay for the measurement of cathepsin B .
Cat. No.: HY-P4340
CAS No.: 263843-55-6
Cat. No.: HY-P4369
CAS No.: 88937-61-5
Cat. No.: HY-P4428A
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
