L-Arginine-7-amido-4-methylcoumarin hydrochloride
Based on 1 Customer Validation
L-Arginine-7-amido-4-methylcoumarin (Arginine 4-methyl-7-coumarylamide) hydrochloride is a specific substrate of cathepsin H but not for cathepsins L and B.
For research use only. We do not sell to patients.
- Purity : 99.87%
- CAS No.: 69304-16-1
- Formula: C16H22ClN5O3
- Molecular Weight:367.83
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Cathepsin Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 69304-16-1
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Appearance Solid
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Molecular Weight 367.83
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Formula C16H22ClN5O3
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Color White to off-white
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SMILES
CC(C1=CC=C(NC([C@@H](N)CCCNC(N)=N)=O)C=C1O2)=CC2=O.Cl
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Synonyms
Arginine 4-methyl-7-coumarylamide hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
H2O : 50 mg/mL (135.93 mM; Need ultrasonic)
DMSO : 3.85 mg/mL (10.47 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 2.7186 mL | 13.5932 mL | 27.1865 mL | 67.9662 mL |
| 5 mM | 0.5437 mL | 2.7186 mL | 5.4373 mL | 13.5932 mL | |
| 10 mM | 0.2719 mL | 1.3593 mL | 2.7186 mL | 6.7966 mL | |
| H2O | 15 mM | 0.1812 mL | 0.9062 mL | 1.8124 mL | 4.5311 mL |
| 20 mM | 0.1359 mL | 0.6797 mL | 1.3593 mL | 3.3983 mL | |
| 25 mM | 0.1087 mL | 0.5437 mL | 1.0875 mL | 2.7186 mL | |
| 30 mM | 0.0906 mL | 0.4531 mL | 0.9062 mL | 2.2655 mL | |
| 40 mM | 0.0680 mL | 0.3398 mL | 0.6797 mL | 1.6992 mL | |
| 50 mM | 0.0544 mL | 0.2719 mL | 0.5437 mL | 1.3593 mL | |
| 60 mM | 0.0453 mL | 0.2266 mL | 0.4531 mL | 1.1328 mL | |
| 80 mM | 0.0340 mL | 0.1699 mL | 0.3398 mL | 0.8496 mL | |
| 100 mM | 0.0272 mL | 0.1359 mL | 0.2719 mL | 0.6797 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.