34 Results for "

Cdh17

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "Cdh17" in MCE Product Catalog:

Cat. No.: HY-P991728
CAS No.: 3038456-02-6
Synonyms: TORL-3-600 antibody

Target:  

Cadherin ADC Antibodies

Research Areas:  

Cancer

Zarutatug (TORL-3-600 antibody) is an IgG1κ humanized antibody targeting cadherin 17 (CDH17). It selectively binds to cell-surface CDH17, triggering endocytosis and trafficking to lysosomes. Zarutatug can be used to construct ADCs, such as TORL-3-600 .
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Cat. No.: HY-P990363
Synonyms: PTA001_A4

Target:  

Cadherin

Research Areas:  

Cancer

Anti-CDH17/Cadherin-17 Antibody (PTA001_A4) is a CHO-expressed human-mouse chimeric antibody targeting CDH17/Cadherin-17. Anti-CDH17/Cadherin-17 Antibody (PTA001_A4) contains an IgG1-type heavy chain and a kappa-type light chain, with a predicted molecular weight (MW) of 149.12 kDa.
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Cat. No.: HY-175615
CAS No.: 3051815-39-2
Research Areas:  

Cancer

RSL3-NH2 is a GPX4 inhibitor and ferroptosis inducer. RSL3-NH2 triggers the iron-dependent cell death pathway associated with lipid peroxidation by inhibiting GPX4 activity. RSL3-NH2 exhibits significant cytotoxicity against colorectal cancer cells and effectively induces their ferroptosis. RSL3-NH2 can serve as a ADC payload for synthesizing antibody-drug conjugates (ADC) and be used in colorectal cancer-related research .
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Cat. No.: HY-P991100

Target:  

Cadherin

Research Areas:  

Cancer

Anti-CDH17/Cadherin-17 Antibody (10C12) is a human antibody expressed in CHO cells, targeting CDH17/Cadherin-17. Anti-CDH17/Cadherin-17 Antibody (10C12) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001). Anti-CDH17/Cadherin-17 Antibody (10C12) can be used in the study of cancer .
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Cat. No.: HY-RS02327
Research Areas:  

Others

CDH17 Human Pre-designed siRNA Set A contains three designed siRNAs for CDH17 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P990730
CAS No.: 2755301-09-6
Synonyms: ARB202

Target:  

CD3 Cadherin

Research Areas:  

Cancer

Cabotamig is a humanized bispecific T-cell engager antibody targeting CDH17/CD3. Cabotamig is generated from anti-CDH17 monoclonal ARB102 by linking a CD3-binding scFv in the format of IgG4-scFv. Cabotamig can be used for the research of cancer, such as gastric cancer and colon cancers .
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Cat. No.: HY-P10941A
Target:  

Integrin FAK ERK

Research Areas:  

Inflammation/Immunology Cancer

VSLRGDTRG acetate is a synthetic peptide containing the RGD motif from cadherin 17 (CDH17), which binds to α2β1 integrin and activates its signaling pathway. VSLRGDTRG acetate promotes the high-affinity conformational change of β1 integrin through the RGD motif, enhancing cell adhesion and phosphorylation of FAK and ERK1/2, thereby driving tumor proliferation and metastasis. VSLRGDTRG acetate can be used in research on cancers expressing CDH17, such as colon cancer and pancreatic cancer .
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Cat. No.: HY-P10941
CAS No.: 2027476-29-3
Target:  

Integrin FAK ERK

Research Areas:  

Inflammation/Immunology Cancer

VSLRGDTRG is a synthetic peptide containing the RGD motif from cadherin 17 (CDH17), which binds to α2β1 integrin and activates its signaling pathway. VSLRGDTRG promotes the high-affinity conformational change of β1 integrin through the RGD motif, enhancing cell adhesion and phosphorylation of FAK and ERK1/2, thereby driving tumor proliferation and metastasis. VSLRGDTRG can be used in research on cancers expressing CDH17, such as colon cancer and pancreatic cancer .
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Cat. No.: HY-RS23619
Research Areas:  

Others

Cdh17 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cdh17 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17169
Research Areas:  

Others

Cdh17 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cdh17 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-187637
CAS No.: 1918106-06-5
Target:  

Topoisomerase

Research Areas:  

Cancer

Govitecan is a topoisomerase I inhibitor and also a linker-payload compound for antibody-drug conjugates (ADCs), with SN-38 as its active component. Govitecan serves as the linker-drug moiety of ADCs targeting CDH17-expressing cancer cells. Govitecan acts as the cytotoxic payload component of ADCs targeting Trop-2. Govitecan can be used in research related to colorectal cancer, gastric cancer, pancreatic cancer, liver cancer, metastatic triple-negative breast cancer, and other conditions .
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Cat. No.: HY-P81964
Synonyms: Cadherin 17; Cdh17; HPT 1; LI-cadherin; Liver Cadherin; liver inTine cadherin

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human

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Cat. No.: HY-P76755
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Cdh17; Human Intestinal Peptide-Associated Transporter HPT-1; Cadherin 17; Human Peptide Transporter 1; Liver-Intestine Cadherin; HPT-1 Cadherin; Cadherin-17; LI Cadherin; HPT-1; Cadherin-16; Intestinal Peptide-Associated Transporter HPT-1; LI-Cadherin; C
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P704422
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Cdh17; Human Intestinal Peptide-Associated Transporter HPT-1; Cadherin 17; Human Peptide Transporter 1; Liver-Intestine Cadherin; HPT-1 Cadherin; Cadherin-17; LI Cadherin; HPT-1; Cadherin-16; Intestinal Peptide-Associated Transporter HPT-1; LI-Cadherin; C
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P77309
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Cdh17; Human Intestinal Peptide-Associated Transporter HPT-1; Cadherin 17; Human Peptide Transporter 1; Liver-Intestine Cadherin; HPT-1 Cadherin; Cadherin-17; LI Cadherin; HPT-1; Cadherin-16; Intestinal Peptide-Associated Transporter HPT-1; LI-Cadherin; C
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P704141
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Cdh17; Human Intestinal Peptide-Associated Transporter HPT-1; Cadherin 17; Human Peptide Transporter 1; Liver-Intestine Cadherin; HPT-1 Cadherin; Cadherin-17; LI Cadherin; HPT-1; Cadherin-16; Intestinal Peptide-Associated Transporter HPT-1; LI-Cadherin; C
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P7699
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Cdh17; Human Intestinal Peptide-Associated Transporter HPT-1; Cadherin 17; Human Peptide Transporter 1; Liver-Intestine Cadherin; HPT-1 Cadherin; Cadherin-17; LI Cadherin; HPT-1; Cadherin-16; Intestinal Peptide-Associated Transporter HPT-1; LI-Cadherin; C
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704986
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Cdh17; Human Intestinal Peptide-Associated Transporter HPT-1; Cadherin 17; Human Peptide Transporter 1; Liver-Intestine Cadherin; HPT-1 Cadherin; Cadherin-17; LI Cadherin; HPT-1; Cadherin-16; Intestinal Peptide-Associated Transporter HPT-1; LI-Cadherin; C
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704423
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Cdh17; Human Intestinal Peptide-Associated Transporter HPT-1; Cadherin 17; Human Peptide Transporter 1; Liver-Intestine Cadherin; HPT-1 Cadherin; Cadherin-17; LI Cadherin; HPT-1; Cadherin-16; Intestinal Peptide-Associated Transporter HPT-1; LI-Cadherin; C
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P77895
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Cdh17; Human Intestinal Peptide-Associated Transporter HPT-1; Cadherin 17; Human Peptide Transporter 1; Liver-Intestine Cadherin; HPT-1 Cadherin; Cadherin-17; LI Cadherin; HPT-1; Cadherin-16; Intestinal Peptide-Associated Transporter HPT-1; LI-Cadherin; C
Species:  
Mouse
Source:  
HEK293
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