Cadherin-17 Protein, Mouse (HEK293, hFc)
Cadherin-17 protein mediates cell-cell interactions by selectively binding to other cadherin-17 proteins in a homophilic manner. This interaction promotes connections between adjacent cells and helps sort and organize different cell types within the tissue. Cadherin-17 Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived Cadherin-17 protein, expressed by HEK293, with C-hFc labeled tag.
- Species: Mouse
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
Cadherin-17 protein mediates cell-cell interactions by selectively binding to other cadherin-17 proteins in a homophilic manner. This interaction promotes connections between adjacent cells and helps sort and organize different cell types within the tissue. Cadherin-17 Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived Cadherin-17 protein, expressed by HEK293, with C-hFc labeled tag.
Background
Cadherin-17 is a calcium-dependent cell adhesion protein that plays a crucial role in cell-to-cell interactions. It exhibits a preferential interaction with other cadherin-17 proteins in a homophilic manner, facilitating the connection between neighboring cells. This specific interaction enables cadherin-17 to contribute to the sorting and organization of diverse cell types within tissues. In particular, LI-cadherin, a subtype of cadherin-17, has been implicated in the morphological organization of liver and intestine, suggesting its involvement in the structural arrangement of these organs.
Technical Parameters
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Species Mouse
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Source HEK293
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Tag C-hFc
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Accession
Q9R100 (F26-M786)
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Gene ID12557
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Molecular Construction
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N-term
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Cadherin-17 (F26-M786)
Accession # Q9R100 -
hFc
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C-term
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Protein Length
Extracellular Domain
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Synonyms
CDH17; Human Intestinal Peptide-Associated Transporter HPT-1; Cadherin 17; Human Peptide Transporter 1; Liver-Intestine Cadherin; HPT-1 Cadherin; Cadherin-17; LI Cadherin; HPT-1; Cadherin-16; Intestinal Peptide-Associated Transporter HPT-1; LI-Cadherin; C
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AA Sequence
FSGPLKPMTFSIFEGQEPSQVIFQFKTNPPAVTFELTGETDGIFKIEKDGLLYHTRALDRETRAVHHLQLAALDSHGAIVDGPVPITIEVKDINDNRPTFLQSKYEGSVRQNSRPGKPFMYVNATDLDDPATPNGQLFYQIVIQLPQINDVMYFQIDSKTGAISLTPEGSQELDPVKNPSYNLVVSVKDMGGQSENSFSDTTYVDISIRENIWKAPEPVEIRENSTDPHPIKITQVQWNDPGAQYSLVNKEKLSPFPFSIDQEGNIYVTQALDREEKNSHVFFATAKDENGKPLAYPLEIYVKVIDINDNPPTCLSPVTVFEVQENEPLGNSIGIFEAHDMDEANNINSILKYKLVDQTPKVPSDGLFLIGEYEGKVQLSKQSLKKQDSPQYNLSIEVSDVDFKTLCYIQVNVIDINDQIPIFETSNYGSKTLSEDTAIGSTILIIQATDADEPFTGSSKILYKIVQGDTEGRLEVVTDPTTNAGYVKIKKPLDFETQPVSSIVFQAENPEPLVKGIEYNASSFASFELIVTDVNEVPVFPQRIFQANVSEDAAVGSRVGNVTARDPEGLTVSYSLKGNMRGWLKIDSVTGEIFSAAPLDRETESVYRVQVVATEVGGSSLSSTADFHLVLTDVNDNPPRLAKDYTGLFFCHPLSAPGSLIFEVTDDDQQSLRRPKFTFALGREGLQSDWEVSKINGTHARLSTRHTRFEEQVYNIPIRINDGGQPPMEGTVFLPVTFCQCVEGSCFRPAGRQDGIPTVGM
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Predicted Molecular Mass
110.8 kDa
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Molecular Weight
Approximately 50 kDa & 110-130 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Glycosylation
Yes
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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