1. Recombinant Proteins
  2. Receptor Proteins
  3. Cell Adhesion Molecules (CAMs)
  4. Cadherins
  5. LI-Cadherin/Cadherin-17
  6. Cadherin-17 Protein, Human (765a.a, HEK293, His)

Cadherin-17 Protein, Human (765a.a, HEK293, His)

Cat. No.: HY-P7699
COA Handling Instructions

Cadherin-17 Protein, Human (765a.a, HEK293, His) is a recombinant human Cadherin-17 produced in HEK293 cells, with His tag. Cadherin-17 is a calcium-dependent transmembrane glycoprotein that mediates cell-cell adhesion in intestinal epithelium.

For research use only. We do not sell to patients.

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10 μg $158 In-stock
50 μg $441 In-stock
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Description

Cadherin-17 Protein, Human (765a.a, HEK293, His) is a recombinant human Cadherin-17 produced in HEK293 cells, with His tag. Cadherin-17 is a calcium-dependent transmembrane glycoprotein that mediates cell-cell adhesion in intestinal epithelium[1].

Background

Cadherin-17, also called liver-intestinal cadherin or human peptide transporter-1, is a member of the cadherin superfamily and is a Ca2+-dependent cell-cell adhesion molecule[1].

Species

Human

Source

HEK293

Tag

C-6*His

Accession

AAI13465.1 (Q23-M787)

Gene ID
Molecular Construction
N-term
Cadherin-17 (Q23-M787)
Accession # Q12864
6*His
C-term
Synonyms
Cadherin-17; CDH17; Intestinal Peptide-Associated Transporter HPT-1; Liver-intestine cadherin (LI-cadherin)
AA Sequence

QEGKFSGPLKPMTFSIYEGQEPSQIIFQFKANPPAVTFELTGETDNIFVIEREGLLYYNRALDRETRSTHNLQVAALDANGIIVEGPVPITIEVKDINDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLYYQIVIQLPMINNVMYFQINNKTGAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDIIVTENIWKAPKPVEMVENSTDPHPIKITQVRWNDPGAQYSLVDKEKLPRFPFSIDQEGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDINDNPPTCPSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLIQTYAGMLQLAKQSLKKQDTPQYNLTIEVSDKDFKTLCFVQINVIDINDQIPIFEKSDYGNLTLAEDTNIGSTILTIQATDADEPFTGSSKILYHIIKGDSEGRLGVDTDPHTNTGYVIIKKPLDFETAAVSNIVFKAENPEPLVFGVKYNASSFAKFTLIVTDVNEAPQFSQHVFQAKVSEDVAIGTKVGNVTAKDPEGLDISYSLRGDTRGWLKIDHVTGEIFSVAPLDREAGSPYRVQVVATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGSLIFEATDDDQHLFRGPHFTFSLGSGSLQNDWEVSKINGTHARLSTRHTDFEEREYVVLIRINDGGRPPLEGIVSLPVTFCSCVEGSCFRPAGHQTGIPTVGMHHHHHH

Molecular Weight

110-130 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Appearance

Lyophilized powder

Formulation

Lyophilized after extensive dialysis against 20 mM PB,150 mM NaCl, pH7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation
References

Cadherin-17 Protein, Human (765a.a, HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Cadherin-17 Protein, Human (765a.a, HEK293, His)
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