15 Results for "

Collagen-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "Collagen-IN-1" in MCE Product Catalog:

Cat. No.: HY-146332
CAS No.: 104260-73-3
Target:  

P-selectin

Research Areas:  

Cardiovascular Disease

Collagen-IN-1 (compound 3), an ortho-carbonyl hydroquinone derivative, is a selective inhibitor on collagen. Collagen-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner with an IC50 value of 1.77 μM. Collagen-IN-1 reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelet. Collagen-IN-1 has the potential for platelet-related thrombosis diseases research [1].
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3
3 Cited Publications
Cat. No.: HY-119358
CAS No.: 6402-36-4
Purity:  99.85%
Traumatic Acid is a wound healing agent and a cytokinin (phytohormone). Traumatic Acid enhances the biosynthesis of collagen in cultured human skin fibroblasts. Traumatic Acid inhibits MCF-7 breast cancer cells viability and enhances apoptosis and oxidative stress. Traumatic Acid can be used in studies of cancer, circulatory disorders (including arterial hypertension), and skin diseases associated with oxidative stress and impaired collagen biosynthesis .
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3
3 Cited Publications
Cat. No.: HY-P1868
CAS No.: 134580-64-6
Synonyms: DGEA peptide
Target:  

Integrin

Research Areas:  

Infection

α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors .
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3
3 Cited Publications
Cat. No.: HY-P1868A
Synonyms: DGEA peptide TFA
Target:  

Integrin

Research Areas:  

Others

α2β1 Integrin Ligand Peptide TFA interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors .
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2
2 Cited Publications
Cat. No.: HY-100495
CAS No.: 1001288-58-9
Purity:  99.32%
Synonyms: Asengeprast
Target:  

MMP

Research Areas:  

Inflammation/Immunology

FT011 is an anti-fibrotic agent, reduces mRNA expression of collagens I and III and inhibits collagen synthesis . FT011 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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1
1 Cited Publications
Cat. No.: HY-P2738
CAS No.: 9007-34-5
Collagen, Type I, from bovine achilles tendon are extracellular matrix proteins and show many applications in food, cosmetic, pharmaceutical and biomedical industries. This product is enzymatically hydrolyzed collagen peptide .
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Cat. No.: HY-158225
Synonyms: Col1MA
Methacrylated Type I collagen (Col1MA) is a methacrylated tissue engineering scaffold material that retains the basic properties of natural collagen [1]. Methacrylated Type I collagen needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity.
Application: cell culture, biological 3D printing, tissue engineering, etc.
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Cat. No.: HY-145358
CAS No.: 2415941-98-7
Target:  

PI3K

Research Areas:  

Cancer

FAP-PI3KI1 is a fibroblast-activated protein (FAP)-targeted PI3K inhibitor that selectively targets FAP-expressing human idiopathic pulmonary fibrosis (IPF) cells and effectively inhibits collagen synthesis and reduces collagen deposition .
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Cat. No.: HY-121311
CAS No.: 81043-56-3
Metrenperone is an inhibitor for 5-HT2 receptor. Metrenperone exhibits α1 and α2 antagonist activity as well as anti-H1 and anti-dopaminergic efficacy. Metrenperone can lower the blood pressure, enhances bradycardia in peripheral ischemia, inhibits serotonin-induced platelet aggregation, and antagonizes serotonin-mediated vasoconstriction. Metrenperone promotes the repair of acutely damaged collagen tissue .
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Cat. No.: HY-P2883A
Recombinant Human Keratin2 is a type II or neutral basic keratin intermediate filament protein that protects against collagen loss .
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Cat. No.: HY-N13220
Target:  

Others

Research Areas:  

Endocrinology

Soybean Extract is a soybean extract, and its components include: Isoflavone. Soybean Extract has an increased content of isoflavone aglycones after biotransformation, which is an estrogen-like bioactive compound with effective type I collagen enhancement. .
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Cat. No.: HY-W404758
CAS No.: 23351-51-1
Research Areas:  

Metabolic Disease

Calcium glucoheptonate is a highly water-soluble calcium supplement. Calcium glucoheptonate can increase the proliferation rate and Calcium intake of MG-63 cells and increase the activity of alkaline phosphatase (ALP). Calcium glucoheptonate can upregulate the expression of osteogenic-related genes and proteins,such as collagen-1, osteocalcin and osteocalcin. Calcium glucoheptonate can be used for the researches of osteoporosis and hypocalcemia [1].
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Cat. No.: HY-182608
0.1% gelatin solution, for cell culture is a biochemical reagent commonly used in cell culture, whose main component is high-molecular-weight polypeptides obtained by hydrolysis of animal collagen. 0.1% gelatin solution, for cell culture can be used to coat the surfaces of cell culture plates, Petri dishes and other vessels to promote the adhesion and proliferation of mammalian cells [1] .
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Cat. No.: HY-100495R
CAS No.: 1001288-58-9
Synonyms: Asengeprast (Standard)
Target:  

MMP Reference Standards

Research Areas:  

Inflammation/Immunology

FT011 (Standard) is the analytical standard of FT011 (HY-100495). This product is intended for research and analytical applications. FT011 is an anti-fibrotic agent, reduces mRNA expression of collagens I and III and inhibits collagen synthesis . FT011 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-P992066

Research Areas:  

Inflammation/Immunology

Anti-Mouse DDR2 Antibody (DAB0065) is a mAb that specifically targets mouse discoidin domain receptor DDR2 without cross-reacting with DDR1. Anti-Mouse DDR2 Antibody (DAB0065) binds to the extracellular domain of native mouse DDR2, induces endocytosis and lysosomal degradation of DDR2, and this process is independent of collagen binding. Anti-Mouse DDR2 Antibody (DAB0065) exhibits significant therapeutic effects in both the unilateral ureteral obstruction (UUO) mouse model of renal fibrosis and the bleomycin (HY-108345)-induced mouse model of pulmonary fibrosis, effectively downregulating the mRNA expression of type I collagen Col1a1 and fibronectin Fn1. Anti-Mouse DDR2 Antibody (DAB0065) can be humanized and has the potential to be developed as a targeted agent for diseases such as idiopathic pulmonary fibrosis and renal fibrosis [1] .
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