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FT011 

Cat. No.: HY-100495 Purity: 99.24%
Handling Instructions

FT011 is an anti-fibrotic agent, reduces mRNA expression of collagens I and III and inhibits collagen synthesis.

For research use only. We do not sell to patients.

FT011 Chemical Structure

FT011 Chemical Structure

CAS No. : 1001288-58-9

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 139 In-stock
Estimated Time of Arrival: December 31
2 mg USD 120 In-stock
Estimated Time of Arrival: December 31
5 mg USD 180 In-stock
Estimated Time of Arrival: December 31
10 mg USD 288 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1092 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1920 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

FT011 is an anti-fibrotic agent, reduces mRNA expression of collagens I and III and inhibits collagen synthesis[1].

In Vivo

FT011 (100 mg/kg b.i.d., p.o., for 4 weeks) improves the cardiac function and and myocardial remodeling in myocardial infarction rats[1].

Animal Model: Seventy male Sprague Dawley (SD) rats (weighing 200-250 g)[1]
Dosage: 100 mg/kg
Administration: B.I.D., p.o. on day 7 after surgery, for 4 weeks
Result: Increased ejection fraction, fraction shortening and preload recruitable stroke work.
Molecular Weight

351.35

Formula

C₂₀H₁₇NO₅

CAS No.

1001288-58-9

SMILES

O=C(O)C1=CC=CC=C1NC(/C=C/C2=CC=C(OCC#C)C(OC)=C2)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 29 mg/mL (82.54 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8462 mL 14.2308 mL 28.4616 mL
5 mM 0.5692 mL 2.8462 mL 5.6923 mL
10 mM 0.2846 mL 1.4231 mL 2.8462 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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FT011
Cat. No.:
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