2415941-98-7
Chemical Structure
FAP-PI3KI1
- CAS No.: 2415941-98-7
- Formula:C52H48F4N10O12S3
- Molecular Weight:1177.19
IUPAC Name: N-(4-(((4-(((S)-1-((S)-2-cyano-4,4-difluoropyrrolidin-1-yl)-1-oxopropan-2-yl)carbamoyl)pyridin-2-yl)methyl)amino)-4-oxobutanoyl)-S-((2-((((5-(6-(5-((2,4-difluorophenyl)sulfonamido)-6-methoxypyridin-3-yl)quinolin-4-yl)pyridin-2-yl)methoxy)carbonyl)oxy)ethy
InChIKey: DXXIUVWNTLDCDL-QWSSMIDASA-N
SMILES: O=C(N1[C@@H](CC(F)(C1)F)C#N)[C@H](C)NC(C2=CC=NC(CNC(CCC(N[C@H](C(O)=O)CSSCCOC(OCC3=NC=C(C4=CC=NC5=C4C=C(C6=CN=C(OC)C(NS(=O)(C7=C(C=C(C=C7)F)F)=O)=C6)C=C5)C=C3)=O)=O)=O)=C2)=O
Biological Activity: FAP-PI3KI1 is a fibroblast-activated protein (FAP)-targeted PI3K inhibitor that selectively targets FAP-expressing human idiopathic pulmonary fibrosis (IPF) cells and effectively inhibits collagen synthesis and reduces collagen deposition[1].
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FAP-PI3KI1 | FAP-PI3KI1 is a fibroblast-activated protein (FAP)-targeted PI3K inhibitor that selectively targets FAP-expressing human idiopathic pulmonary fibrosis (IPF) cells and effectively inhibits collagen synthesis and reduces collagen deposition. | |||||||||||||||||||||
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