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Corynebacterium

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AMPK (1) Antibiotic (6) Apoptosis (3) Autophagy (2) Bacterial (12) Biochemical Assay Reagents (4) Endogenous Metabolite (2) Environmental Pollutants (1) Fluorescent Dye (1) Fungal (1) NF-κB (1) p38 MAPK (1) PGC-1α (1) Phosphodiesterase (PDE) (1) Reference Standards (2) Topoisomerase (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (2) Infection (16) Inflammation/Immunology (5) Metabolic Disease (3)

Inhibitors & Agonists

Fluorescent Dyes

Natural
Products

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0435

Roxithromycin 5+ Cited Publications RU-28965	Bacterial Antibiotic Apoptosis p38 MAPK NF-κB	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Roxithromycin (RU-28965) is an orally active semi-synthethic macrolide antibiotic. Roxithromycin inhibits protein biosynthesis in the elongation step by binding to 50S bacterial ribosome. Roxithromycin has antimicrobial, antiproliferative, anti-inflammatory, tumour vasculature inhibiting and lung injury ameliorating effects .

HY-D2919

DMN-Tre	Fluorescent Dye	Infection
DMN-Tre is a conjugate of a solvatochromic fluorescent dye and trehalose. DMN-Tre takes advantage of the substrate promiscuity of the endogenous antigen 85 protein complex in mycobacteria to be metabolically integrated into the hydrophobic mycobacterial membrane. Once entering this hydrophobic environment, the linked DMN dye fluorescence is "turned on", enabling specific labeling . DMN-Tre can be used to reflect bacterial metabolic activity and support physiological studies of Mycobacterium tuberculosis .

HY-N3686

D-Arabitol	AMPK PGC-1α	Metabolic Disease
D-Arabitol is an orally active D-enantiomer of arabitol. D-Arabitol modulates the composition of gut microbiota, increases short-chain fatty acids, and promotes AMPK-PGC-1α-related browning of white adipose tissue. D-Arabitol improves weight gain, fat accumulation, insulin resistance, lipid deposition and inflammatory responses. D-Arabitol serves as the sole carbon/energy source for Bacillus methanolicus MGA3, a strain that can co-utilize it with mannitol. D-Arabitol is applicable to obesity-related research .

HY-N1416

Pogostone 2 Publications Verification	Bacterial Apoptosis Autophagy	Infection Inflammation/Immunology Cancer
Pogostone is isolated from patchouli oil with anti-bacterial and anti-cancer activities. Pogostone inhibits both gram negative and gram positive bacteria, also show inhibitory effect on corynebacterium xerosis with a MIC value of 0.098 µg/ml . Pogostone induces cell apoptosis and autophagy .

HY-B2072A

Cephaloridine hydrate	Antibiotic Bacterial	Infection
Cephaloridine hydrate is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity .

HY-19393

SCH 351591	Phosphodiesterase (PDE)	Cardiovascular Disease Inflammation/Immunology Cancer
SCH 351591 is a highly selective, orally active PDE4 inhibitor, with IC₅₀ values of 58 nM and 153 nM in humans and rats, respectively. SCH 351591 effectively inhibits pathological processes such as cytokine production, eosinophilia, airway hyperresponsiveness and bronchospasm. SCH 351591 also induces microvascular injury, activates mast cells and endothelial cells, and causes increases in serum histamine and various inflammatory factors, leading to early vascular damage. SCH 351591 has been widely used in studies related to asthma, chronic obstructive pulmonary disease and drug-induced vascular injury .

HY-106526

Xibornol Bactacine; Nanbacine	Bacterial	Infection Inflammation/Immunology
Xibornol (Bactacine) has strong antibacterial action against Streptococcus pneumoniae, Streptococcus pyogenes, and Staphyloccus aureus, as well as against Actinomyces israelii and Corynebacterium ulcerans. Xibornol has the potential for using for the antisepsis of the oral cavity and as adjuvant in pharyngeal infections caused by Gram-positive microorganisms .

HY-B2072

Cephaloridine	Antibiotic Bacterial	Infection
Cephaloridine is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity .

HY-N15184

Benanomicin B Pradimicin C	Bacterial Fungal	Infection
Benanomicin B (Pradimicin C) is an antifungal antibiotic that also has antibacterial activity against two Gram-positive bacteria: Micrococcus luteus and Corynebacterium bovis .

HY-N1416R

Pogostone (Standard)	Reference Standards Bacterial Apoptosis Autophagy	Infection Inflammation/Immunology
Pogostone (Standard) is the analytical standard of Pogostone. This product is intended for research and analytical applications. Pogostone is isolated from patchouli oil?with anti-bacterial and anti-cancer activities.?Pogostone inhibits both gram negative and gram positive bacteria, also show inhibitory effect on corynebacterium xerosis with a MIC value of 0.098 μg/ml .?Pogostone induces cell apoptosis and autophagy .

HY-126746

Corynecin I	Antibiotic	Infection
Corynecin I is an antibiotic produced by Corynebacterium hydrocarboclastus, and its precursor (D-(-) threo-p-amino phenyl serinol-N-acetylamine) has a minimal inhibitory effect on the synthesis of Corynecin from mevalonic acid .

HY-123598

Corynecin III	Antibiotic Bacterial	Infection
Corynecin III is a Chloramphenicol (HY-B0239)-like antibiotic, which is found in Corynebacterium. Corynecin III inhibits the growth of Gram-positive and Gram-negative bacteria with MIC values of 2.6-83 μg/mL .

HY-B2072AR

Cephaloridine hydrate (Standard)	Reference Standards Antibiotic Bacterial	Infection
Cefadroxil (hydrate) (Standard) is the analytical standard of Cefadroxil (hydrate). This product is intended for research and analytical applications. Cefadroxil hydrate (BL-S 578 hydrate) is an orally active and first-generation cephalosporin with a broad spectrum antibacterial activity. Cefadroxil hydrate (BL-S 578 hydrate) also acts as a substrate of the peptide transporter PEPT1 and PEPT2 .

HY-E70082A

*Fructosyl-Amino Acid Oxidase, Corynebacterium* sp.**	Biochemical Assay Reagents	Others
Fructosyl-Amino Acid Oxidase, Corynebacterium sp. catalyzes the oxidative deglycation of low molecular weight fructosamines. Fructosyl-Amino Acid Oxidase, Corynebacterium sp. catalyzes the oxidation of the C-N bond linking the C1 of the fructosyl moiety and the nitrogen of the amino group of fructosyl amino acids.

HY-135849E

*Catalase, Corynebacterium* sp.**	Biochemical Assay Reagents	Metabolic Disease
Catalase, Corynebacterium sp. (EC 1.11.1.6) activates the decomposition of hydrogen peroxide, a reactive oxygen species, into water and oxygen. Catalase functions as a natural antioxidant, protecting cells against oxidative damage to proteins, lipids and nucleic acids.

HY-135849D

*Catalase, Corynebacterium* glutamicum**	Biochemical Assay Reagents	Metabolic Disease
Catalase, Corynebacterium glutamicum (EC 1.11.1.6) activates the decomposition of hydrogen peroxide, a reactive oxygen species, into water and oxygen. Catalase functions as a natural antioxidant, protecting cells against oxidative damage to proteins, lipids and nucleic acids.

HY-180414

Premafloxacin	Bacterial Topoisomerase	Infection
Premafloxacin is a potent antimicrobial agent that exhibits activity against Staphylococcus aureus, Corynebacterium bovis, and Corynebacterium amylocolatum. Premafloxacin demonstrated potent antimicrobial activity against S. aureus by targeting topoisomerase IV, and is a poor substrate for NorA efflux pump. Premafloxacin can be used for antimicrobial research .

HY-126747

Corynecin IV	Endogenous Metabolite	Infection
Corynecin IV is a chloramphenicol-like bacterial metabolite originally isolated from Corynebacterium .

HY-126745

Corynecin V	Endogenous Metabolite	Infection
Corynecin V is a chloramphenicol-like bacterial metabolite originally isolated from Corynebacterium .

HY-D3391

RMR-Tre	Bacterial	Infection
RMR-Tre is a fluorescent probe targeting the mycobacterial acyltransferase Ag85. Under the catalysis of Ag85, RMR-Tre undergoes 6-position mycoloylation and anchors to the mycobacterial membrane, while achieving fluorescence activation by inhibiting the intramolecular twisted charge transfer state transition. RMR-Tre can distinguish live mycobacteria from dead ones through metabolism-driven labeling, enabling rapid, wash-free, low-background detection of viable bacteria. RMR-Tre reports the drug resistance of Mycobacterium tuberculosis via the trehalose catalytic shift activity readout associated with TreS. In addition, RMR-Tre can be combined with flow cytometry or high-content imaging techniques to visualize and quantitatively analyze the metabolic heterogeneity of Mycobacterium tuberculosis related to persistence and drug resistance. RMR-Tre is widely used in tuberculosis-related research .

HY-Y1805

Tetralin 1,2,3,4-Tetrahydronaphthalene	Environmental Pollutants Biochemical Assay Reagents Bacterial	Infection
Tetralin (1,2,3,4-Tetrahydronaphthalene) is an Antibacterial agent. Tetralin inhibits the growth of E. coli and Arthrobacter strain T2. Tetralin serves as a probe molecule for cracking and hydrotreating the light cycle oil .

Cat. No.	Product Name	Type

HY-D2919

DMN-Tre	Fluorescent Dyes
DMN-Tre is a conjugate of a solvatochromic fluorescent dye and trehalose. DMN-Tre takes advantage of the substrate promiscuity of the endogenous antigen 85 protein complex in mycobacteria to be metabolically integrated into the hydrophobic mycobacterial membrane. Once entering this hydrophobic environment, the linked DMN dye fluorescence is "turned on", enabling specific labeling . DMN-Tre can be used to reflect bacterial metabolic activity and support physiological studies of Mycobacterium tuberculosis .

DMN-Tre

Fluorescent Dyes

DMN-Tre is a conjugate of a solvatochromic fluorescent dye and trehalose. DMN-Tre takes advantage of the substrate promiscuity of the endogenous antigen 85 protein complex in mycobacteria to be metabolically integrated into the hydrophobic mycobacterial membrane. Once entering this hydrophobic environment, the linked DMN dye fluorescence is "turned on", enabling specific labeling . DMN-Tre can be used to reflect bacterial metabolic activity and support physiological studies of Mycobacterium tuberculosis .

HY-D3391

RMR-Tre	Fluorescent Dyes
RMR-Tre is a fluorescent probe targeting the mycobacterial acyltransferase Ag85. Under the catalysis of Ag85, RMR-Tre undergoes 6-position mycoloylation and anchors to the mycobacterial membrane, while achieving fluorescence activation by inhibiting the intramolecular twisted charge transfer state transition. RMR-Tre can distinguish live mycobacteria from dead ones through metabolism-driven labeling, enabling rapid, wash-free, low-background detection of viable bacteria. RMR-Tre reports the drug resistance of Mycobacterium tuberculosis via the trehalose catalytic shift activity readout associated with TreS. In addition, RMR-Tre can be combined with flow cytometry or high-content imaging techniques to visualize and quantitatively analyze the metabolic heterogeneity of Mycobacterium tuberculosis related to persistence and drug resistance. RMR-Tre is widely used in tuberculosis-related research .

RMR-Tre

Fluorescent Dyes

RMR-Tre is a fluorescent probe targeting the mycobacterial acyltransferase Ag85. Under the catalysis of Ag85, RMR-Tre undergoes 6-position mycoloylation and anchors to the mycobacterial membrane, while achieving fluorescence activation by inhibiting the intramolecular twisted charge transfer state transition. RMR-Tre can distinguish live mycobacteria from dead ones through metabolism-driven labeling, enabling rapid, wash-free, low-background detection of viable bacteria. RMR-Tre reports the drug resistance of Mycobacterium tuberculosis via the trehalose catalytic shift activity readout associated with TreS. In addition, RMR-Tre can be combined with flow cytometry or high-content imaging techniques to visualize and quantitatively analyze the metabolic heterogeneity of Mycobacterium tuberculosis related to persistence and drug resistance. RMR-Tre is widely used in tuberculosis-related research .

D-Arabitol	Structural Classification Endogenous metabolite Saccharides Source Classification	AMPK PGC-1α
D-Arabitol is an orally active D-enantiomer of arabitol. D-Arabitol modulates the composition of gut microbiota, increases short-chain fatty acids, and promotes AMPK-PGC-1α-related browning of white adipose tissue. D-Arabitol improves weight gain, fat accumulation, insulin resistance, lipid deposition and inflammatory responses. D-Arabitol serves as the sole carbon/energy source for Bacillus methanolicus MGA3, a strain that can co-utilize it with mannitol. D-Arabitol is applicable to obesity-related research .

Pogostone 2 Publications Verification	Natural Products Entada phaseoloides (L.) Merr. Classification of Application Fields Labiatae Plants Inflammation/Immunology Disease Research Fields Source Classification	Bacterial Apoptosis Autophagy
Pogostone is isolated from patchouli oil with anti-bacterial and anti-cancer activities. Pogostone inhibits both gram negative and gram positive bacteria, also show inhibitory effect on corynebacterium xerosis with a MIC value of 0.098 µg/ml . Pogostone induces cell apoptosis and autophagy .

Benanomicin B Pradimicin C	Microorganisms Antibiotics Source Classification	Bacterial Fungal
Benanomicin B (Pradimicin C) is an antifungal antibiotic that also has antibacterial activity against two Gram-positive bacteria: Micrococcus luteus and Corynebacterium bovis .

Pogostone (Standard)	Structural Classification Natural Products Entada phaseoloides (L.) Merr. Labiatae Plants Source Classification	Reference Standards Bacterial Apoptosis Autophagy
Pogostone (Standard) is the analytical standard of Pogostone. This product is intended for research and analytical applications. Pogostone is isolated from patchouli oil?with anti-bacterial and anti-cancer activities.?Pogostone inhibits both gram negative and gram positive bacteria, also show inhibitory effect on corynebacterium xerosis with a MIC value of 0.098 μg/ml .?Pogostone induces cell apoptosis and autophagy .

Corynecin I	Natural Products Microorganisms Source Classification	Antibiotic
Corynecin I is an antibiotic produced by Corynebacterium hydrocarboclastus, and its precursor (D-(-) threo-p-amino phenyl serinol-N-acetylamine) has a minimal inhibitory effect on the synthesis of Corynecin from mevalonic acid .

Corynecin III	Natural Products Microorganisms Source Classification	Antibiotic Bacterial
Corynecin III is a Chloramphenicol (HY-B0239)-like antibiotic, which is found in Corynebacterium. Corynecin III inhibits the growth of Gram-positive and Gram-negative bacteria with MIC values of 2.6-83 μg/mL .

Tag:	His (2) Tag Free (2) Flag (1)
Source:	E. coli (4)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P701949

	*panD Protein, Corynebacterium* jeikeium** panD; Aspartate 1-decarboxylase; Aspartate alpha-decarboxylase	Others	E. coli
	The panD protein plays a crucial role in cellular metabolism by catalyzing the pyruvyl-dependent decarboxylation of aspartate, thereby producing β-alanine. This enzyme activity represents a key step in the biosynthesis of pantothenic acid (vitamin B5), since beta-alanine is the precursor for the formation of this important cofactor. panD Protein, Corynebacterium jeikeium is the recombinant panD protein, expressed by E. coli , with tag free.

HY-P701950

	*panD Protein, Corynebacterium* jeikeium (FLAG, His)** panD; Aspartate 1-decarboxylase; Aspartate alpha-decarboxylase	Others	E. coli
	The panD protein plays a crucial role in cellular metabolism by catalyzing the pyruvyl-dependent decarboxylation of aspartate, thereby producing β-alanine. This enzyme activity represents a key step in the biosynthesis of pantothenic acid (vitamin B5), since beta-alanine is the precursor for the formation of this important cofactor. panD Protein, Corynebacterium jeikeium (FLAG, His) is the recombinant panD protein, expressed by E. coli , with N-6*His, N-Flag labeled tag.

HY-P702121

	*fum Protein, Corynebacterium* glutamicum** fumC; Fumarate hydratase class II; Fumarase C; Aerobic fumarase; Iron-independent fumarase	Others	E. coli
	Fum proteins crucially catalyze the interconversion of fumarate to L-malate in the tricarboxylic acid (TCA) cycle, maintaining metabolite flow in cellular energy metabolism. This critical step, if precisely regulated, helps generate energy and generates intermediates critical to cellular processes. fum Protein, Corynebacterium glutamicum is the recombinant fum protein, expressed by E. coli , with tag free.

HY-P702122

	*fum Protein, Corynebacterium* glutamicum (His)** fumC; Fumarate hydratase class II; Fumarase C; Aerobic fumarase; Iron-independent fumarase	Others	E. coli
	Fum proteins crucially catalyze the interconversion of fumarate to L-malate in the tricarboxylic acid (TCA) cycle, maintaining metabolite flow in cellular energy metabolism. This critical step, if precisely regulated, helps generate energy and generates intermediates critical to cellular processes. fum Protein, Corynebacterium glutamicum (His) is the recombinant fum protein, expressed by E. coli , with N-6*His labeled tag.

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Corynebacterium

Inhibitors & Agonists

Fluorescent Dyes

NaturalProducts

Recombinant Proteins

Natural
Products