1. Anti-infection
  2. Antibiotic Bacterial
  3. Cephaloridine

Cephaloridine is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Cephaloridine hydrate) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Cephaloridine Chemical Structure

Cephaloridine Chemical Structure

CAS No. : 50-59-9

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Description

Cephaloridine is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity[1][2].

IC50 & Target

β-lactam

 

In Vitro

Cephaloridine can inhibit Staphylococcus aureus penicillin-sensitive strains, penicillin-resistant strains, Streptococcus pyogenes, Streptococcus pneumoniae, Corynebacterium diphtheriae, Clostridium septicum, and so on, with MICs of 0.05-1 μg/mL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Cephaloridine (50-500 mg/kg; i.m.) exhibits dose-related nephrotoxicity in rabbits and monkeys[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Rabbits and monkeys[2]
Dosage: 50, 100, 200 and 500 mg/kg
Administration: i.m.
Result: Resulted in marked alteration in renal function and necrosis of proximal tubules at 200 and 500 mg/kg.
Did not appear to cause renal injury at 50 and 100 mg/kg.
Molecular Weight

415.49

Formula

C19H17N3O4S2

CAS No.
SMILES

O=C(C(N12)=C(C[N+]3=CC=CC=C3)CS[C@]2([H])[C@H](NC(CC4=CC=CS4)=O)C1=O)[O-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Cephaloridine Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Cephaloridine
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HY-B2072
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