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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
Curvularia lunata
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "Curvularia lunata" in MCE Product Catalog:
Category:
Cardiovascular Disease Veratrum nigrum Linn. Liliaceae Plants Disease Research Fields Steroids
Target:
Cat. No.: HY-N6770
CAS No.: 10140-70-2
Synonyms: (S)-Curvularin
Category:
Infection Microorganisms Macrolide Antibiotics Antifungal Antibiotics Phenols Polyphenols Disease Research Disease Research Fields
Target:
Cat. No.: HY-W017143
CAS No.: 27593-23-3
Category:
Target:
Cat. No.: HY-187993
Target:
Research Areas:
SDH-IN-47 is a succinate dehydrogenase (SDH) inhibitor, with an IC50 value of 1.80 μM against SDH from Botrytis cinerea. SDH-IN-47 binds to the active site of SDH, interferes with fungal growth, disrupts mycelial morphology and cell membrane integrity, and induces depolarization of mitochondrial membrane potential. SDH-IN-47 exhibits in vitro and in vivo antifungal activities against a variety of plant pathogenic fungi, including Botrytis cinerea, Phytophthora capsici, and Valsa mali, and can be used for studies on related fungal infections .
Cat. No.: HY-184420
CAS No.: 1822599-86-9
Research Areas:
Antimicrobial agent-51 is an antifungal agent that increases ROS levels, reduces mitochondrial membrane potential, alters hyphal morphology, and impairs cell membrane integrity. Antimicrobial agent-51 inhibits succinate dehydrogenase (SDH) with an IC50 of 0.76 μg/mL against Colletotrichum gloeosporioides. Antimicrobial agent-51 exhibits control efficacy against Alternaria solani on tomato fruits and shows low toxicity to plant and mammalian cells. Antimicrobial agent-51 can be used for the research of plant fungal diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
