10140-70-2
10140-70-2
Chemical Structure
Curvularin
Synonym(s): (S)-Curvularin
- CAS No.: 10140-70-2
- Formula:C16H20O5
- Molecular Weight:292.33
IUPAC Name: (S)-11,13-dihydroxy-4-methyl-4,5,6,7,8,9-hexahydro-2H-benzo[d][1]oxacyclododecine-2,10(1H)-dione
InChIKey: VDUIGYAPSXCJFC-JTQLQIEISA-N
SMILES: O=C(O[C@@H](C)CCCCC1)CC2=CC(O)=CC(O)=C2C1=O
Biological Activity: Curvularin, a fungal metabolite and a potent mycotoxin naturally isolated from Curvularia lunata, inhibits cytokine-induced nitric oxide synthase (iNOS), with an IC50 of 9.5 µM[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Curvularin | 99.99% | Curvularin, a fungal metabolite and a potent mycotoxin naturally isolated from Curvularia lunata, inhibits cytokine-induced nitric oxide synthase (iNOS), with an IC50 of 9.5 µM. | ||||||||||||||||||||
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References
- [1]. Kumar CG, et al. Metabolite profiling and biological activities of bioactive compounds produced by Chrysosporium lobatum strain BK-3 isolated from Kaziranga National Park, Assam, India. Springerplus. 2013 Dec;2(1):122. [Content Brief]
- [2]. Yao Y, et al. Sporogen, S14-95, and S-curvularin, three inhibitors of human inducible nitric-oxide synthase expression isolated from fungi. Mol Pharmacol. 2003 Feb;63(2):383-91. [Content Brief]
Keywords
