33 Results for "

D-erythro-Sphingosine

" in MedChemExpress (MCE) Product Catalog:
Products (33)

33 Results for "D-erythro-Sphingosine" in MCE Product Catalog:

6
6 Publications Verification
Cat. No.: HY-101047
CAS No.: 123-78-4
Purity:  ≥98.0%
Synonyms: erythroSphingosine; erythro-C18-Sphingosine; trans-4-Sphingenine
D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator .
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6
6 Publications Verification
Cat. No.: HY-W089922
CAS No.: 2673-72-5
Synonyms: erythroSphingosine hydrochloride; erythro-C18-Sphingosine hydrochloride; trans-4-Sphingenine hydrochloride
Category:  

Animals

Target:  

TRP Channel

D-erythro-Sphingosine (Erythrosphingosine) hydrochloride is a specific TRPM3 activator. D-erythro-Sphingosine also induces retinoblastoma protein dephosphorylation .
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1
1 Cited Publications
Cat. No.: HY-101047S
CAS No.: 1246304-34-6
Purity:  99.00%
Synonyms: erythroSphingosine-d7; erythro-C18-Sphingosine-d7; trans-4-Sphingenine-d7
D-erythro-Sphingosine-d7 is the deuterium labeled D-erythro-Sphingosine. D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator .
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1
1 Cited Publications
Cat. No.: HY-100353
CAS No.: 74713-60-3
Purity:  99.82%
Synonyms: N-Lauroyl-D-erythro-Sphingosine; N-LaurylSphingosine
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease Cancer

C12-Ceramide (N-Lauroyl-D-erythro-sphingosine), a naturally occurring ceramide, is formed by hydrolysis of C12 sphingomyelin. C12-Ceramide can enhance the Doxorubicin toxicity in MDA-MB-231 cells. C12-Ceramide also can be used to diagnose types A and B Niemann-Pick disease .
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Cat. No.: HY-154831
CAS No.: 27888-44-4
Purity:  ≥98.0%
Synonyms: N-Behenoyl-D-erythro-Sphingosine; C22-Ceramide; Cer d18:1/22:0
Target:  

Liposome

C22-Ceramide (d18:1/22:0) (N-Behenoyl-D-erythro-sphingosine) is an ultra-long-chain ceramide containing a C22:0 behenoyl acyl chain. C22-Ceramide can be glycosylated via CGT-3 to form C22 glucosylceramide (C22 GlcCer), which in turn maintains clathrin membrane localization and lysosomal homeostasis, inhibits TOR signaling and promotes SKN-1 activation, thereby enhancing oxidative stress resistance and extending the lifespan of C. elegans. C22-Ceramide can be used in research on cardiometabolic diseases such as type 2 diabetes, obesity, dyslipidemia, coronary artery disease and thin-cap fibroatheroma (TCFA), as well as oxidative stress and aging-related studies .
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Cat. No.: HY-115703
CAS No.: 67492-16-4
Synonyms: N-Heptadecanoyl-D-erythro-Sphingosine
Research Areas:  

Metabolic Disease

C17 Ceramide (d18:1/17:0) (N-Heptadecanoyl-D-erythro-sphingosine) is a phospholipid internal standard. C17 Ceramide (d18:1/17:0) is used in studies of medium-chain acyl-CoA dehydrogenase deficiency (MCADD) .
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Cat. No.: HY-108391
CAS No.: 74713-59-0
Purity:  ≥98.0%
Synonyms: N-Octanoyl-D-erythro-Sphingosine
Target:  

Apoptosis PKC Autophagy

Research Areas:  

Inflammation/Immunology Cancer

C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) is a cell-permeable analog of naturally occurring ceramides. C8-Ceramide has anti-proliferation properties and acts as a potent chemotherapeutic agent. C8-Ceramide stimulates dendritic cells to promote T cell responses upon virus infections. C8-Ceramide induces slight activation of protein kinase (PKC) in vitro .
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Cat. No.: HY-170035
CAS No.: 95119-86-1
Synonyms: C18 Glucosyl(β) ceramide (d18:1/18:0); D-glucosyl-β-1,1' N-stearoyl-D-erythro-Sphingosine
Target:  

Fungal Wnt β-catenin

Research Areas:  

Infection Neurological Disease Cancer

GlcCer (d18:1/18:0) (C18 Glucosyl(β) ceramide (d18:1/18:0)) is a glycosphingolipids that activates the Wnt/β-catenin pathway by targeting LRP6. GlcCer (d18:1/18:0) drives EMT, migration, invasion and GBA1-mediated liver cancer metastasis. GlcCer (d18:1/18:0) accumulates to impair lysosomal function and induce toxic α-synuclein aggregation. GlcCer (d18:1/18:0) supports growth, sporulation, germination and virulence in Penicillium digitatum. GlcCer (d18:1/18:0) is reduced in demyelinated mouse corpus callosum. GlcCer (d18:1/18:0) can be used for the research of liver cancer, synucleinopathies, fungal, Parkinson’s disease and Gaucher disease .
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Cat. No.: HY-101047R
CAS No.: 123-78-4
Synonyms: erythroSphingosine (Standard); erythro-C18-Sphingosine (Standard); trans-4-Sphingenine (Standard)
D-erythro-Sphingosine (Standard) is the analytical standard of D-erythro-Sphingosine. This product is intended for research and analytical applications. D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator[1][2][3][4].
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Cat. No.: HY-141630
CAS No.: 474923-27-8
Purity:  99.00%
Synonyms: D-erythro-Sphingosine-C17-1-phosphate
Target:  

Drug Derivative

Research Areas:  

Cancer

Sphingosine-1-phosphate d17:1 (D-erythro-Sphingosine-C17-1-phosphate) is a derivative of ceramide. Sphingosine-1-phosphate d17:1 can be used for the research of cancer .
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Cat. No.: HY-N10636
CAS No.: 125712-73-4
Target:  

Drug Derivative

Research Areas:  

Others

D-lactosyl-β-1,1′ N-stearoyl-D-erythro-sphingosine is a neutral glycolipid .
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Cat. No.: HY-134104
CAS No.: 6918-49-6
Synonyms: D-erythro-Sphingosine-C20
C20-Sphingosine is a long-chain base (LCB) that can be used in the study of neural development .
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Cat. No.: HY-165550
CAS No.: 134053-67-1
Synonyms: C22-D-erythro-Sphingosine
Sphingosine (C22-D-erythro-Sphingosine) is a metabolite of sphingolipid and a pro-Apoptotic signaling messenger. Sphingosine induces apoptosis via Caspase-dependent, mitochondria-dependent and lysosomal affinity detergent pathways, downregulates Bcl-2 and Bcl-xL, and truncates Bid and Bax. Sphingosine is used for cancer research .
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Cat. No.: HY-W654343
CAS No.: 2734928-88-0
D-Erythro-sphingosine-1-phosphate- 13C2,d2 is 13C labeled D-Erythro-sphingosine-1-phosphate .
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Cat. No.: HY-101047S1
CAS No.: 2692623-81-5
Synonyms: erythroSphingosine-13C2,d2; erythro-C18-Sphingosine-13C2,d2; trans-4-Sphingenine-13C2,d2
D-erythro-Sphingosine-13C2,d2 is a deuterated labeled D-erythro-Sphingosine . D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator .
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Cat. No.: HY-146908S
Research Areas:  

Others

N-Pentadecanoyl-D-erythro-sphingosine-d7 is deuterium labeled N-Pentadecanoyl-D-erythro-sphingosine.
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Cat. No.: HY-W344461
CAS No.: 74713-58-9
Synonyms: N-Butyryl-D-erythro-Sphingosine
Research Areas:  

Metabolic Disease

N-Butyroyl-D-sphingosine (N-Butyryl-D-erythro-sphingosine) is an ester product.
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Cat. No.: HY-146922S
CAS No.: 2770684-23-4
D-Galactosyl-ß-1,1' N-nervonoyl-D-erythro-sphingosine-d7 is deuterium labeled D-Galactosyl-ß-1,1' N-nervonoyl-D-erythro-sphingosine.
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Cat. No.: HY-146923S
CAS No.: 2770684-31-4
D-Lactosyl-ß-1,1' N-nervonoyl-D-erythro-sphingosine-d7 is deuterium labeled D-Lactosyl-ß-1,1' N-nervonoyl-D-erythro-sphingosine.
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Cat. No.: HY-146764S
CAS No.: 2315262-20-3
D-Lactosyl-β-1,1'-N-pentadecanoyl-D-erythro-sphingosine-d7 is deuterium labeled D-Lactosyl-β-1,1'-N-pentadecanoyl-D-erythro-sphingosine.
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