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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
D5D inhibitor
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "D5D inhibitor" in MCE Product Catalog:
2
2 Cited Publications
Target:
Research Areas:
D5D-IN-326 is a selective, orally active delta-5 desaturase (D5D) inhibitor, with IC50s of 72 and 22 nM for rat and human D5D in enzymic and cell-based assays, respectively, has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistance and decreases body weight in diet-induced obese C57BL/6J mice .
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1 Cited Publications
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Research Areas:
T-3364366 is a reversible, slow-binding, thienopyrimidinone delta-5 desaturase (D5D) inhibitor with IC50s of 1.9 nM and 2.1 nM in HepG2 and RLN-10 cells, respectively. T-3364366 exhibits potent D5D (IC500=19 nM) inhibitory activity and excellent selectivity away from delta-6 desaturase (D6D, IC50=6200 nM) and delta-9 desaturase (stearoyl-CoA desaturase, SCD,50 >10000 nM) in the enzymatic activity assay .
Cat. No.: HY-13636S1
Synonyms: ICI 182780-d5; ZD 9238-d5; ZM 182780-d5
Cat. No.: HY-113422S
CAS No.: 2483831-29-2
Cat. No.: HY-W011235S
CAS No.: 1188265-34-0
Cat. No.: HY-A0003S
CAS No.: 1227162-34-6
Synonyms: CC-5013-d5
Lenalidomide-d5 (CC-5013-d5) is the d5-labeled Lenalidomide (HY-A0003). Lenalidomide (CC-5013) is an orally active immunomodulatory agent that binds CRBN as a molecular glue to alter substrate specificity, inducing ubiquitination and proteasome-dependent degradation of IKZF1, IKZF3 and CK1α. Lenalidomide induces apoptosis by degrading IKZF1/3, and activates p53 by degrading CK1α. Lenalidomide promotes IL-2 release and effector functions of CD8 + T/NK cells, while inhibiting TNF-α secretion and M1-type pyroptosis. Lenalidomide can be used in research related to hematological malignancies, acute liver failure and acute kidney injury .
Cat. No.: HY-101873S
Cat. No.: HY-10211S
Synonyms: 17-AAG-d5; NSC 330507-d5; CP 127374-d5
Cat. No.: HY-135556AS
CAS No.: 1185132-92-6
Cat. No.: HY-10572S
CAS No.: 1132642-95-5
Cat. No.: HY-10284S4
Synonyms: BI 1356-d5
Cat. No.: HY-14268S3
Synonyms: TEI 6720-d5; TMX 67-d5
Cat. No.: HY-145399S
Synonyms: SG 3932-d5; AZ-0133-d5
Cat. No.: HY-17474S1
Synonyms: SC 69124-d5
Cat. No.: HY-13204AS
CAS No.: 2938691-75-7
Synonyms: KL 373-d5
Cat. No.: HY-119684S
Cat. No.: HY-116214S
CAS No.: 1773496-67-5
Synonyms: CGA-219417-d5
Cat. No.: HY-70057S4
Synonyms: FCE 26743-d5; EMD 1195686-d5
Cat. No.: HY-N0176S3
Synonyms: Dihydroqinghaosu-d5; β-Dihydroartemisinin-d5; Artenimol-d5
Cat. No.: HY-10570S3
CAS No.: 1189717-29-0
Synonyms: BI-RG 587-d5; NSC 641530-d5; NVP-d5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
