Norfluoxetine-d5 hydrochloride
Based on 1 Customer Validation
Norfluoxetine-d5 hydrochloride is the d5-labeled Norfluoxetine hydrochloride (HY-W011235). Norfluoxetine hydrochloride is the active metabolite of the antidepressant Fluoxetine (HY-B0102); it is also a TREK-2 K2P potassium channel inhibitor. Norfluoxetine hydrochloride exhibits neuroimmunological activity, induces apoptosis in primary microglial cells, and inhibits the release of pro-inflammatory factors. Norfluoxetine hydrochloride inhibits high-threshold voltage-gated Ca2+ currents in neurons with an EC50 of 20.4 μM. Norfluoxetine hydrochloride can be used in research related to depression, ischemic stroke, and epilepsy.
For research use only. We do not sell to patients.
- Purity: 99.30%
- CAS No.: 1188265-34-0
- Formula: C16H12D5ClF3NO
- Molecular Weight:336.79
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1188265-34-0
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Unlabeled Cas 83891-03-6
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Appearance Solid
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Molecular Weight 336.79
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Formula C16H12D5ClF3NO
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Color White to off-white
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SMILES
FC(F)(F)C(C=C1)=CC=C1OC(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])CCN.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 125 mg/mL (371.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9692 mL | 14.8460 mL | 29.6921 mL | 74.2302 mL |
| 5 mM | 0.5938 mL | 2.9692 mL | 5.9384 mL | 14.8460 mL | |
| 10 mM | 0.2969 mL | 1.4846 mL | 2.9692 mL | 7.4230 mL | |
| 15 mM | 0.1979 mL | 0.9897 mL | 1.9795 mL | 4.9487 mL | |
| 20 mM | 0.1485 mL | 0.7423 mL | 1.4846 mL | 3.7115 mL | |
| 25 mM | 0.1188 mL | 0.5938 mL | 1.1877 mL | 2.9692 mL | |
| 30 mM | 0.0990 mL | 0.4949 mL | 0.9897 mL | 2.4743 mL | |
| 40 mM | 0.0742 mL | 0.3712 mL | 0.7423 mL | 1.8558 mL | |
| 50 mM | 0.0594 mL | 0.2969 mL | 0.5938 mL | 1.4846 mL | |
| 60 mM | 0.0495 mL | 0.2474 mL | 0.4949 mL | 1.2372 mL | |
| 80 mM | 0.0371 mL | 0.1856 mL | 0.3712 mL | 0.9279 mL | |
| 100 mM | 0.0297 mL | 0.1485 mL | 0.2969 mL | 0.7423 mL |
Norfluoxetine-d5 hydrochloride Related Classifications
HY-W011235S Related Classifications
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