1236767-85-3
Chemical Structure
D5D-IN-326
- CAS No.: 1236767-85-3
- Formula:C17H11F8N3O4
- Molecular Weight:473.27
IUPAC Name: 2-(2,2,3,3,3-pentafluoropropoxy)-3-(4-(2,2,2-trifluoroethoxy)phenyl)-5,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-4,6-dione
InChIKey: NGUQGJZXDBRNOL-UHFFFAOYSA-N
SMILES: O=C1C2=C(N=C(N1C3=CC=C(C=C3)OCC(F)(F)F)OCC(F)(C(F)(F)F)F)NC(C2)=O
Biological Activity: D5D-IN-326 is a selective, orally active delta-5 desaturase (D5D) inhibitor, with IC50s of 72 and 22 nM for rat and human D5D in enzymic and cell-based assays, respectively, has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistance and decreases body weight in diet-induced obese C57BL/6J mice[1].
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D5D-IN-326 | 99.90% | D5D-IN-326 is a selective, orally active delta-5 desaturase (D5D) inhibitor, with IC50s of 72 and 22 nM for rat and human D5D in enzymic and cell-based assays, respectively, has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistance and decreases body weight in diet-induced obese C57BL/6J mice. | ||||||||||||||||||||
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