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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
DHODH-IN-1
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "DHODH-IN-1" in MCE Product Catalog:
Research Areas:
DHODH-IN-1 (compound 18d) is a potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 25 nM. DHODH-IN-1 is an inhibitor of pyrimidine biosynthesis pathway [1].
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5 Cited Publications
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Tenovin-1, a p53 activator, protects p53 from MDM2-mediated degradation. Tenovin-1 acts through inhibition of the protein-deacetylating activities of SirT1 and SirT2. Tenovin-1 is also a dihydroorotate dehydrogenase (DHODH) inhibitor .
Cat. No.: HY-N7961
CAS No.: 102811-39-2
Category:
Monophenols Ginkgoaceae Ketones, Aldehydes, Acids Other Diseases Phenols Ginkgo biloba L. Plants Disease Research Fields
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Cat. No.: HY-142843
CAS No.: 2764662-15-7
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RORγt/DHODH-IN-1 (compound (R)-14d) is a potent and orally active dual RORγt/DHODH inhibitor, with IC50s of 0.083 μM and 0.172 μM, respectively. RORγt/DHODH-IN-1 exhibits remarkable in vivo anti-inflammatory activity [1].
Cat. No.: HY-169220S
CAS No.: 3000567-76-7
Cat. No.: HY-176728
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DHODH-IN-27 (WF-8) is a dihydroacetate dehydrogenase (DHODH) inhibitor with an IC50 of 64.97 μM. DHODH-IN-27 can be used as an anti-DHODH herbicide .
Cat. No.: HY-117908
CAS No.: 1281861-06-0
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DSM267 is a triazolopyrimidine inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH), with an IC50 of 38 nM, while its IC50 against human DHODH exceeds 100000 nM. DSM267 is used for the in vitro systematic screening and characterization of the resistance evolution pathways of Plasmodium falciparum to DHODH inhibitors .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
