3000567-76-7
3000567-76-7
Chemical Structure
RORγ/DHODH-IN-1
- CAS No.: 3000567-76-7
- Formula:C23H13D2Cl2F4N3O2
- Molecular Weight:514.30
InChIKey: NRVNUOYPOQZERF-ZWGOZCLVSA-N
SMILES: ClC(C=CC=C1F)=C1C2=NOC(C3=C(N(C4=CC(Cl)=CC=C4)N=C3)C(F)(F)F)=C2C([2H])([2H])OC5CC5
Biological Activity: RORγ/DHODH-IN-1 (compound 1404), a deuterium labeled compound, is a dual RORγ and DHODH inhibitor with IC50 values of 9.7 nM and 100 nM, repaectively. RORγ/DHODH-IN-1 blocks the replication of SARS-CoV-2, HCMV, and non-enveloped DNA virus (HAdV5)[1].
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RORγ/DHODH-IN-1 | RORγ/DHODH-IN-1 (compound 1404), a deuterium labeled compound, is a dual RORγ and DHODH inhibitor with IC50 values of 9.7 nM and 100 nM, repaectively. RORγ/DHODH-IN-1 blocks the replication of SARS-CoV-2, HCMV, and non-enveloped DNA virus (HAdV5). | |||||||||||||||||||||
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RORγt inverse agonist 38 | RORγt inverse agonist 38 (C102) is a RORγt inverse agonist. RORγt inverse agonist 38 can be used for the research of psoriasis, autoimmune thyroiditis, inflammatory bowel disease, cancer, and other conditions. | |||||||||||||||||||||
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