1 Result for "

Dual Nav/NMDAR-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Dual Nav/NMDAR-IN-1" in MCE Product Catalog:

Cat. No.: HY-184718
Target:  

Sodium Channel iGluR

Research Areas:  

Neurological Disease

Dual Nav/NMDAR-IN-1 (compound 11a) is a dual-target modulator of Nav and NMDAR. Dual Nav/NMDAR-IN-1 increases the thermal stability of Nav and NMDAR and slows their proteolytic degradation, indicating that it binds to both Nav and NMDAR simultaneously. Dual Nav/NMDAR-IN-1 exhibits anticonvulsant activity in a pentylenetetrazole-induced mouse model of seizures and can be used in epilepsy-related research .
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