1 Result for "

EGFR/HER2/DHFR-IN-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "EGFR/HER2/DHFR-IN-3" in MCE Product Catalog:

Cat. No.: HY-149633
Research Areas:  

Cancer

EGFR/HER2/DHFR-IN-3 (compound 4c) is a potent dual inhibitor of EGFR/HER2, with IC50s of 0.138 and 0.092 μM, respectively. EGFR/HER2/DHFR-IN-3 also inhibits DHFR, with an IC50 of 0.193 M. EGFR/HER2/DHFR-IN-3 causes arrest at the S phase of the cell cycle and induces apoptosis in MCF7 breast cancer cells .
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