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EGFR/HER2/DHFR-IN-3

EGFR/HER2/DHFR-IN-3 (compound 4c) is a potent dual inhibitor of EGFR/HER2, with IC50s of 0.138 and 0.092 μM, respectively. EGFR/HER2/DHFR-IN-3 also inhibits DHFR, with an IC50 of 0.193 M. EGFR/HER2/DHFR-IN-3 causes arrest at the S phase of the cell cycle and induces apoptosis in MCF7 breast cancer cells.

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  • Formel: C22H19N3O3
  • Molecular Weight:373.40
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • EGFR/HER2/DHFR-IN-3 Chemical Structure
    EGFR/HER2/DHFR-IN-3 Chemical Structure
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  • EGFR/HER2/DHFR-IN-3 Chemical Structure
    EGFR/HER2/DHFR-IN-3 Chemical Structure
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  • EGFR/HER2/DHFR-IN-3