1 Result for "

EGFR T790M/L858R-IN-2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "EGFR T790M/L858R-IN-2" in MCE Product Catalog:

Cat. No.: HY-149824
CAS No.: 2955607-40-4
Purity:  99.66%
Target:  

EGFR Apoptosis

Research Areas:  

Cancer

EGFR T790M/L858R-IN-2 is a potent and selective EGFRT790M/L858R inhibitor with IC50 values of 3.5, 1290 nM for EGFRT790M/L858R, EGFR WT, respectively. EGFR T790M/L858R-IN-2 decreases the expression of p-EGFR, P-AKT, P-ERK1/2. EGFR T790M/L858R-IN-2 induces Apoptosis and cell cycle arrest in the G1 phase. EGFR T790M/L858R-IN-2 shows anti-cancer activity .
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