1 Result for "

ER 50891 quarterhydrate

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ER 50891 quarterhydrate" in MCE Product Catalog:

Cat. No.: HY-108531A
Purity:  99.86%
Target:  

RAR/RXR

Research Areas:  

Cancer

ER 50891 quarterhydrate is a RARα antagonist. ER 50891 can significantly antagonize the inhibitory effect of all-trans retinoic acid (ATRA) on the total cell metabolic activity and proliferation of MC3T3-E1 preosteoblasts. ER 50891 rescues ATRA-inhibited osteocalcin (OCN) expression and extracellular matrix mineralization, and suppresses alkaline phosphatase (ALP) activity synergistically. ER 50891 can be used for the study of osteoporosis related to ATRA-induced inhibition of osteoblastogenesis .
loading...
    loading...