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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
EV-A71-IN-1
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "EV-A71-IN-1" in MCE Product Catalog:
Cat. No.: HY-145850
CAS No.: 2413648-96-9
Target:
Research Areas:
EV-A71-IN-1 is a human enterovirus A71 (EV-A71) capsid protein inhibitor with an EC50 of 0.27 μM against EV-A71. EV-A71-IN-1 is a capsid binder that blocks the interaction between the viral VP1 and the host receptor hSCARB2. EV-A71-IN-1 inhibits a series of different human enteroviruses without significant cytotoxicity (CC50>56.2 μM) .
1
1 Cited Publications
Cat. No.: HY-N0620
CAS No.: 102841-43-0
Cat. No.: HY-146009
CAS No.: 2671019-15-9
Target:
Research Areas:
AL-470 is a potent antiviral agent with EC50 values of 0.27, 0.63, and 0.35 µM against HIV-1, HIV-2, and EV-A71, respectively .
Cat. No.: HY-182971
Target:
Research Areas:
PROTAC EV-A71 Degrader-1 is a PROTAC degrader targeting EV-A71 3D polymerase, with broad-spectrum activity against a variety of enteroviruses. PROTAC EV-A71 Degrader-1 induces the degradation of EV-A71 3D polymerase through the ubiquitin-proteasome and autophagy-lysosome pathways, and blocks viral replication. PROTAC EV-A71 Degrader-1 protects infected mice from death, alleviates tissue damage, and exhibits safety profiles. PROTAC EV-A71 Degrader-1 can be used in the research of enterovirus infections .
Cat. No.: HY-182976
CAS No.: 2917501-96-1
Research Areas:
Tenovin-3-CO-C9-NH2 is a conjugate of a target protein ligand and a linker, which can be used for the synthesis of PROTAC EV-A71 Degrader-1 (HY-182971) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
