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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
130 Results for "
Enantiomers
" in MedChemExpress (MCE) Product Catalog:
Products (130)
130 Results for "Enantiomers" in MCE Product Catalog:
7
7 Publications Verification
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YK-4-279 blocks RNA Helicase A (RHA) binding with EWS-FLI1 (oncogenic protein). YK-4-279 induces apoptosis and shows anti-proliferation activities towards various cancer cells. YK-4-279 has a chiral center and it can be separated into two enantiomers. YK-4-279 can be used for the research of cancer .
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3 Cited Publications
Cat. No.: HY-19778
CAS No.: 1415390-47-4
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(R)-BPO-27, the R enantiomer of BPO-27, is a potent, orally active and ATP-competitive CFTR inhibitor with an IC50 of 4 nM.
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1 Cited Publications
Cat. No.: HY-B0105B
CAS No.: 142128-57-2
Synonyms: (-)-Ketoconazole; (-)-Ketoconazol; (-)-R 41400
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Levoketoconazole ((-)-Ketoconazole) is the 2S,4R enantiomer derived from racemic Ketoconazole (HY-B0105). Levoketoconazole is a potent and orally active cortisol synthesis inhibitor. Levoketoconazole inhibits key steps in cortisol and testosterone synthesis by inhibiting CYP11B1, CYP11A1, and CYP17A1. Levoketoconazole can be used for research on endogenous Cushing’s syndrome .
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1 Cited Publications
Cat. No.: HY-A0295
CAS No.: 13071-11-9
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(R)-Propranolol hydrochloride is a less active enantiomer of the β-adrenoceptor antagonist propranolol (HY-B0573). Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively .
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1 Cited Publications
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(S)-(+)-Dimethindene maleate, an enantiomer, is a potent M2-selective muscarinic receptor antagonist (pA2 = 7.86/7.74; pKi = 7.78). (S)-(+)-Dimethindene maleate shows lower affinities for the muscarinic M1 (pA2 = 6.83/6.36; pKi = 7.08), the M3 (pA2 = 6.92/6.96; pKi = 6.70) and the M4 receptors (pKi = 7.00), respectively. (S)-(+)-Dimethindene maleate also is a histamine H1 receptor antagonist (pA2 = 7.48) .
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1 Cited Publications
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RR-RJW100, the enantiomer of RJW100, is an nuclear receptor liver receptor homolog 1 (LRH-1) and steroidogenic factor 1 (SF-1) agonist. RJW100 can be synthesized as two enantiomers, RR-RJW100 and SS-RJW100, with RR-RJW100 shown to be the more potent LRH-1 agonist. RR-RJW100 is involved in the regulation of metabolic homeostasis and is used in studies of diabetes, liver disease and inflammatory bowel disease .
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(S)-Nimodipine ((S)-BAY-e 9736) is an enantiomer of Nimodipine. Nimodipine (BAY-e 9736) is an orally active, well-tolerated and light-sensitive dihydropyridine calcium antagonist. Nimodipine can be used for the research of cerebrovascular disorders .
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Golgicide A-2 (GCA-2), a Golgicide A (GCA) derivative, is the most active enantiomer of GCA. Golgicide A-2 displays high selectivity and efficiency in killing An. stephensi larvae and can be used for the research of dengue virus related diseases .
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1 Cited Publications
Cat. No.: HY-W023323
CAS No.: 925704-45-6
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(S)-β-Aminoisobutyric acid hydrochloride is a cytoprotective agent, which is a non-proteinogenic amino acid enantiomer derived from valine metabolism in skeletal muscle mitochondria. The plasma level of (S)-β-Aminoisobutyric acid hydrochloride increases significantly after acute aerobic exercise (and is not affected by the AGXT2 rs37369 genotype), and it is secreted by mouse extensor digitorum longus and soleus muscles in ex vivo contraction assays. (S)-β-Aminoisobutyric acid hydrochloride specifically protects osteocytes from oxidative stress-induced cell death .
Cat. No.: HY-W048449
CAS No.: 21788-37-4
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L-Biotin is the unnatural enantiomer of Biotin (HY-B0511) .
Cat. No.: HY-D1314
CAS No.: 1386385-76-7
Synonyms: 6-FAM azide
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(R)-Thalidomide ((R)-(+)-Thalidomide) is the R-enantiomer of Thalidomide. (R)-Thalidomide has psychomotor stabilizing properties .
Cat. No.: HY-W012874
CAS No.: 632-20-2
Synonyms: H-D-Thr-OH
Cat. No.: HY-N0424
CAS No.: 84605-18-5
Synonyms: Cyclogalegigenin
Category:
Triterpenes Leguminosae Anti-aging Terpenoids Other Diseases Plants Disease Research Fields Astragalus galegiformis
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Cat. No.: HY-W007337
CAS No.: 627-18-9
Cat. No.: HY-W017442
CAS No.: 3130-87-8
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(2S,3R)-Brassinazole, the enantiomer of Brassinazole (BRZ). Brassinazole inhibits brassinosteroid (BR) biosynthesis, via acting on the oxidative processes from 6-oxo-campestanol to teasterone. (2S,3R)-Brassinazole might be the most active form of Brz .
Cat. No.: HY-I0636
CAS No.: 608141-44-2
Synonyms: (R)-CC-10004
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(R)-Apremilast ((R)-CC-10004) is a enantiomer of Apremilast .
Cat. No.: HY-W010042S3
Synonyms: L-(-)-Glucose-13C6
Cat. No.: HY-15997B
CAS No.: 67197-96-0
Synonyms: (±)-Trans-(1R,2R)-U-50488 hydrochloride
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(±)-U-50488 ((±)-Trans-(1R,2R)-U-50488) hydrochloride is a selective κ opioid receptor (KOR) agonist .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
