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Epimedin A (Standard)

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標的別:	Akt (1) Caspase (2) CDK (1) Heme Oxygenase (HO) (1) Interleukin Related (1) Keap1-Nrf2 (2) NF-κB (1) NOD-like Receptor (NLR) (1) PI3K (1) Reference Standards (4) SOD (1)
研究分野別:	Cancer (1) Inflammation/Immunology (2) Metabolic Disease (1)

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製品番号	製品名	Target	研究分野	構造式

HY-N0257R

Epimedin A (Standard)	Reference Standards PI3K Akt NF-κB NOD-like Receptor (NLR) Keap1-Nrf2 Heme Oxygenase (HO) SOD Caspase Interleukin Related	Metabolic Disease Inflammation/Immunology
Epimedin A (Standard) is the analytical standard of Epimedin A (HY-N0257). This product is intended for research and analytical applications. Epimedin A, one of the main flavonoid active components in Herba Epimedii, is orally active. Epimedin A can inhibit osteoclastogenesis, differentiation, and bone resorption. Epimedin A also possesses anti-inflammatory activity. Epimedin A can be used in the research of osteoporosis and inflammatory diseases .

HY-N0258R

Epimedin A1 (Standard) Hexandraside F (Standard)	Reference Standards Others	Cancer
Epimedin A1 (Standard) is the analytical standard of Epimedin A1. This product is intended for research and analytical applications. Epimedin A1 is a flavonoid extracted from Herba Epimedii which is one of commonly used Chinese medicines.

HY-N0259R

Epimedin B (Standard) Epmedin B (Standard)	Reference Standards Others	Others
Epimedin B (Standard) is the analytical standard of Epimedin B. This product is intended for research and analytical applications.

HY-N0260R

Epmedin C (Standard) Epimedin-C (Standard); Baohuoside-VI (Standard)	Reference Standards Keap1-Nrf2 CDK Caspase	Inflammation/Immunology
Epmedin C (Standard) is the analytical standard of Epmedin C. This product is intended for research and analytical applications. Epmedin C (Epimedin-C; Baohuoside-VI) is an orally active anti-inflammatory agent and immunomodulator that binds to multiple key proteins including UCP1, Caspase-1, CDK2 and Keap1. Epmedin C inhibits epithelial cell proliferation by disrupting the complex function of CDK2/Cyclin E. Epmedin C also upregulates Nrf2 expression, reduces ROS levels and inhibits pro-inflammatory cytokine secretion, thereby effectively restoring antibody production and alleviating tissue damage. Epmedin C has good safety with no hepatotoxicity or skin sensitization, and it has been used in studies on diseases such as obesity, Deoxynivalenol (HY-N6684)-induced immunotoxicity and mammary hyperplasia .

Epimedin A (Standard)	Flavonols Structural Classification Monophenols Flavonoids Phenols Epimedium brevicornu Maxim. Plants Berberidaceae Source Classification	Reference Standards PI3K Akt NF-κB NOD-like Receptor (NLR) Keap1-Nrf2 Heme Oxygenase (HO) SOD Caspase Interleukin Related
Epimedin A (Standard) is the analytical standard of Epimedin A (HY-N0257). This product is intended for research and analytical applications. Epimedin A, one of the main flavonoid active components in Herba Epimedii, is orally active. Epimedin A can inhibit osteoclastogenesis, differentiation, and bone resorption. Epimedin A also possesses anti-inflammatory activity. Epimedin A can be used in the research of osteoporosis and inflammatory diseases .

Epimedin A1 (Standard) Hexandraside F (Standard)	Flavonols Structural Classification Monophenols Flavonoids Phenols Epimedium brevicornu Maxim. Plants Berberidaceae Source Classification	Reference Standards Others
Epimedin A1 (Standard) is the analytical standard of Epimedin A1. This product is intended for research and analytical applications. Epimedin A1 is a flavonoid extracted from Herba Epimedii which is one of commonly used Chinese medicines.

Epimedin B (Standard) Epmedin B (Standard)	Flavonols Structural Classification Monophenols Flavonoids Phenols Epimedium brevicornu Maxim. Plants Berberidaceae Source Classification	Reference Standards Others
Epimedin B (Standard) is the analytical standard of Epimedin B. This product is intended for research and analytical applications.

Epmedin C (Standard) Epimedin-C (Standard); Baohuoside-VI (Standard)	Flavonols Structural Classification Monophenols Flavonoids Phenols Epimedium brevicornu Maxim. Plants Berberidaceae Source Classification	Reference Standards Keap1-Nrf2 CDK Caspase
Epmedin C (Standard) is the analytical standard of Epmedin C. This product is intended for research and analytical applications. Epmedin C (Epimedin-C; Baohuoside-VI) is an orally active anti-inflammatory agent and immunomodulator that binds to multiple key proteins including UCP1, Caspase-1, CDK2 and Keap1. Epmedin C inhibits epithelial cell proliferation by disrupting the complex function of CDK2/Cyclin E. Epmedin C also upregulates Nrf2 expression, reduces ROS levels and inhibits pro-inflammatory cytokine secretion, thereby effectively restoring antibody production and alleviating tissue damage. Epmedin C has good safety with no hepatotoxicity or skin sensitization, and it has been used in studies on diseases such as obesity, Deoxynivalenol (HY-N6684)-induced immunotoxicity and mammary hyperplasia .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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