4 Results for "

Epimedin A (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Epimedin A (Standard)" in MCE Product Catalog:

Epimedin A (Standard)
Epimedin A (Standard)
0 Images
Cat. No.: HY-N0257R
CAS No.: 110623-72-8
Category:  

Flavonols Flavonoids Monophenols Phenols Epimedium brevicornu Maxim. Plants Berberidaceae

Target:  

Reference Standards PI3K Akt NF-κB NOD-like Receptor (NLR) Keap1-Nrf2 Heme Oxygenase (HO) SOD Caspase Interleukin Related

Epimedin A (Standard) is the analytical standard of Epimedin A (HY-N0257). This product is intended for research and analytical applications. Epimedin A, one of the main flavonoid active components in Herba Epimedii, is orally active. Epimedin A can inhibit osteoclastogenesis, differentiation, and bone resorption. Epimedin A also possesses anti-inflammatory activity. Epimedin A can be used in the research of osteoporosis and inflammatory diseases .
loading...
    loading...
View All Sizes
Epimedin A1 (Standard)
Epimedin A1 (Standard)
0 Images
Cat. No.: HY-N0258R
CAS No.: 140147-77-9
Synonyms: Hexandraside F (Standard)
Category:  

Flavonols Flavonoids Monophenols Phenols Epimedium brevicornu Maxim. Plants Berberidaceae

Target:  

Reference Standards Others

Epimedin A1 (Standard) is the analytical standard of Epimedin A1. This product is intended for research and analytical applications. Epimedin A1 is a flavonoid extracted from Herba Epimedii which is one of commonly used Chinese medicines.
loading...
    loading...
View All Sizes
Epimedin B (Standard)
Epimedin B (Standard)
0 Images
Cat. No.: HY-N0259R
CAS No.: 110623-73-9
Synonyms: Epmedin B (Standard)
Category:  

Flavonols Flavonoids Monophenols Phenols Epimedium brevicornu Maxim. Plants Berberidaceae

Target:  

Reference Standards JNK Estrogen Receptor/ERR p38 MAPK PI3K Akt AMPK Keap1-Nrf2 Reactive Oxygen Species (ROS) Apoptosis Bcl-2 Family

Epimedin B (Standard) (Epmedin B (Standard)) is the analytical standard of Epimedin B (HY-N0259). This product is intended for research and analytical applications. Epimedin B (Epmedin B) is a flavonoid active component found in Epimedium, with oral activity, and exhibits anti-osteoporotic and neuroprotective effects. Epimedin B inhibits RANKL-induced osteoclast differentiation, F-actin ring formation, and mature osteoclast bone resorption, inhibits the phosphorylation of JNK, p38 MAPK, PI3K, and AKT, activates the AMPK-Nrf2 antioxidant pathway, and reduces cellular and mitochondrial ROS. Epimedin B acts on ESR1 and exerts its effects via GPER. Epimedin B alleviates bone loss and improves bone microstructure in vivo, and in Parkinson's models protects dopaminergic neurons and maintains striatal dopamine levels through anti-apoptotic and anti-endoplasmic reticulum stress effects. Epimedin B can be used for research related to osteoporosis, diabetic osteoporosis, and Parkinson's disease .
loading...
    loading...
View All Sizes
Epmedin C (Standard)
Epmedin C (Standard)
0 Images
Cat. No.: HY-N0260R
CAS No.: 110642-44-9
Synonyms: Epimedin-C (Standard); Baohuoside-VI (Standard)
Category:  

Flavonols Flavonoids Monophenols Phenols Epimedium brevicornu Maxim. Plants Berberidaceae

Target:  

Reference Standards Keap1-Nrf2 CDK Caspase

Epmedin C (Standard) is the analytical standard of Epmedin C. This product is intended for research and analytical applications. Epmedin C (Epimedin-C; Baohuoside-VI) is an orally active anti-inflammatory agent and immunomodulator that binds to multiple key proteins including UCP1, Caspase-1, CDK2 and Keap1. Epmedin C inhibits epithelial cell proliferation by disrupting the complex function of CDK2/Cyclin E. Epmedin C also upregulates Nrf2 expression, reduces ROS levels and inhibits pro-inflammatory cytokine secretion, thereby effectively restoring antibody production and alleviating tissue damage. Epmedin C has good safety with no hepatotoxicity or skin sensitization, and it has been used in studies on diseases such as obesity, Deoxynivalenol (HY-N6684)-induced immunotoxicity and mammary hyperplasia .
loading...
    loading...
View All Sizes
Assay Types