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Escherichia coli strain JB1104

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UDP-3-O-acyl-GlcNAc Tris
UDP-3-O-acyl-GlcNAc Tris
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Cat. No.: HY-W585865
CAS No.: 112710-84-6
Synonyms: UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine Tris
Category:  

Infection Natural Products Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Bacterial

UDP-3-O-acyl-GlcNAc Tris (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine Tris) serves as a deacetylation substrate and biosynthetic intermediate in the biosynthetic pathways of lipid A and Kdo2-lipid A in Escherichia coli. UDP-3-O-acyl-GlcNAc Tris undergoes enzymatic deacetylation via LpxC to produce UDP-3-O-[(R)-3-hydroxymyristoyl]glucosamine and release acetate. UDP-3-O-acyl-GlcNAc Tris accumulates in Escherichia coli extracts in the absence of [(R)-3-hydroxymyristoyl]-acyl carrier protein. UDP-3-O-acyl-GlcNAc Tris can be used in studies related to Gram-negative shock .
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