1 Result for "

Faridoxorubicin

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Faridoxorubicin" in MCE Product Catalog:

Cat. No.: HY-177083
CAS No.: 1841402-73-0
Synonyms: AVA-6000
Target:  

FAP

Research Areas:  

Cancer

Faridoxorubicin (AVA-6000) is a FAP-activated chemotherapeutic prodrug. Faridoxorubicin undergoes selective hydrolysis by FAP, while it is resistant to cleavage by related mammalian peptidases and members of the DASH subfamily. Faridoxorubicin acts as a tumor growth inhibitor, reducing tumor volume and prolonging survival in in vivo models and PDX models with high FAP expression. Faridoxorubicin can be used in the research of osteosarcoma and sarcoma .
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