1 Result for "

Fludarabine triphosphate trisodium

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Fludarabine triphosphate trisodium" in MCE Product Catalog:

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1 Cited Publications
Cat. No.: HY-136650A
Purity:  99.56%
Synonyms: F-ara-ATP trisodium
Fludarabine triphosphate (F-ara-ATP) trisodium, the active metabolite of Fludarabine (HY-B0069), is a potent, noncompetitive and specific inhibitor of DNA primase, with an IC50 of 2.3 μM and a Ki of 6.1 μM. Fludarabine triphosphate trisodium inhibits DNA synthesis by blocking DNA primase and primer RNA formation. Fludarabine triphosphate trisodium inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis .
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