1 Result for "

GαoB protein

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GαoB protein" in MCE Product Catalog:

Art. -Nr.: HY-187957
Target:  

mAChR ERK

Forschungsgebiete:  

Neurological Disease

M1/M4 muscarinic agonist 4 is a dual-site muscarinic acetylcholine receptor ligand with potent agonistic activity at M1/M4 muscarinic acetylcholine receptors. M1/M4 muscarinic agonist 4 activates M1R to induce phosphorylation of ERK1/2, and activates M4R to induce GαoB protein activation as well as ERK1/2 phosphorylation. M1/M4 muscarinic agonist 4 exhibits higher binding affinity for M4R than for other muscarinic receptors, while its binding affinity for the W435A mutant M4R is reduced. M1/M4 muscarinic agonist 4 can be used in the research of schizophrenia .
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