1 Result for "

GNE-7056

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GNE-7056" in MCE Product Catalog:

Cat. No.: HY-189477
CAS No.: 1557236-81-3
GNE-7056 is an orally active interleukin-2-inducible T-cell kinase (ITK) inhibitor with a Ki of 0.2 nM against human kinase, and exhibits high selectivity over LCK kinase. GNE-7056 inhibits PLCγ-1 phosphorylation, suppresses the production of IL-2, IL-4, IL-13 and TH2 cytokines, reduces CD4 + T-cell proliferation, and inhibits activation-induced cell death of CD4 + T cells by decreasing the abundance of FasL. GNE-7056 can be used in asthma-related research .
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