1 Result for "

HG-03 human liver microsomes

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "HG-03 human liver microsomes" in MCE Product Catalog:

(-)-Fenchone
(-)-Fenchone
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Cat. No.: HY-N5132
CAS No.: 7787-20-4
Category:  

Other Monoterpenes Terpenoids Other Diseases Plants Umbelliferae Vernonia Schreb. Disease Research Fields

Target:  

Cytochrome P450

(-)-Fenchone is a bicyclic monoterpene and serves as a substrate for human liver microsomal cytochrome P450 enzymes CYP2A6 and CYP2B6. (-)-Fenchone is not metabolized by human CYP1A1, CYP1A2, CYP1B1, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, or CYP3A4 enzymes. (-)-Fenchone undergoes hydroxylation to produce 6-exo-hydroxyfenchone, 6-endo-hydroxyfenchone, and 10-hydroxyfenchone. During the metabolism of (-)-Fenchone, CYP2A6 may play a more important role than CYP2B6 .
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