1 Result for "

HPK1-IN-56

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HPK1-IN-56" in MCE Product Catalog:

Cat. No.: HY-172107
CAS No.: 2901054-39-3
Research Areas:  

Inflammation/Immunology Cancer

HPK1-IN-56 (Compound A29) is a HPK1 inhibitor (IC50: 2.70 nM). HPK1-IN-56 inhibits downstream p-SLP76 (IC50: 8.1 nM in Jurkat T cells). HPK1-IN-56 induces the production of IL-2 in human PBMCs. HPK1-IN-56 has anticancer effect, enhances T-cell killing ability and the antitumor efficacy of anti-PD-1 antibody .
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