7 Results for "

HPV16 E6

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "HPV16 E6" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-163901
CAS No.: 945142-65-4
Target:  

HPV Apoptosis

Research Areas:  

Infection Cancer

E6-272 is a human papillomavirus 16 (HPV 16) inhibitor. E6-272 induces Apoptosis. E6-272 inhibits the proliferation of HPV-positive cells. E6-272 can be used in the research of cervical cancer .
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Cat. No.: HY-P10428
Target:  

HPV

Research Areas:  

Infection

E6AP-mimicking peptide (compound 13) is a high-affinity, selective, irreversible and potent peptide-based covalent HPV16 E6 inhibitor targeting the 16E6 oncoprotein using a cysteine-reactive acrylamide warhead. E6AP-mimicking peptide has a Ki of 17 nM. E6AP-mimicking peptide targets all residues appearing in the binding pocket of E6 to disrupt the binding interface of 16E6 and E6AP. E6AP-mimicking peptide selectively binds and crosslinks to MBP-16E6 in PBS or a protein mixture .
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Cat. No.: HY-P89419

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, FC, IF-Tissue

Reactivity:  

Virus

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Cat. No.: HY-N20712
CAS No.: 59632-76-7
Anisomelic acid is a human papillomavirus HPV16 E6 and HPV E7 depletor . Anisomelic acid directly interacts with HPV16 E6, promotes its ubiquitination and proteasomal degradation by recruiting E3 ubiquitin ligase, downregulates E6 and facilitates E7 degradation. Anisomelic acid induces endogenous mitochondrial apoptosis, activates caspase-3, causes cleavage of PARP, and triggers p53-independent endogenous apoptosis by depleting cIAP2. Anisomelic acid can be used in research related to HPV-positive cancers and cervical cancer .
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Cat. No.: HY-P72260
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Protein E6; E6
Species:  
Virus
Source:  
E. coli
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Cat. No.: HY-P700914
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Human papillomavirus type 16; HPV16; E6
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P700915
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Human papillomavirus type 16; HPV16; E6
Species:  
Human
Source:  
HEK293
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