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HepG2 cell homogenates

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Nombre del producto Target Áreas de investigación Chemical Structure
  • HY-160250
    UGT1A1-IN-1

    		Fluorescent Dye UGT Metabolic Disease
    UGT1A1-IN-1 is a UGT1A1 inhibitor and fluorescent probe (Ex=370 nm, Em=520 nm), with an IC50 of 1.33 μM and a Ki of 5.02 μM. UGT1A1-IN-1 is selectively glucuronidated by UGT1A1 at the bilirubin homologous binding site, and its PET effect is blocked along with this reaction, triggering fluorescence changes. UGT1A1-IN-1 can serve as a substitute for bilirubin to detect UGT1A1 activity and perform high-throughput screening of UGT1A1 modulators .
    UGT1A1-IN-1
  • HY-100303A
    FR194738
    2 Publications Verification

    		 Squalene Monooxygenase Metabolic Disease
    FR194738 is a squalene epoxidase inhibitor. FR194738 inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM.
    FR194738
  • HY-100303
    FR194738 free base
    2 Publications Verification

    		 Squalene Monooxygenase Metabolic Disease
    FR194738 free base is a squalene epoxidase inhibitor. FR194738 inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM.
    FR194738 free base
  • HY-100303AR
    FR194738 (Standard)

    		Others Reference Standards Metabolic Disease
    FR194738 (Standard) is the analytical standard of FR194738 (HY-100303A). This product is intended for research and analytical applications. FR194738 is a squalene epoxidase inhibitor. FR194738 inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM.
    FR194738 (Standard)
  • HY-100303R
    FR194738 free base (Standard)

    		Others Reference Standards Metabolic Disease
    FR194738 free base (Standard) is the analytical standard of FR194738 free base (HY-100303). This product is intended for research and analytical applications. FR194738 free base is a squalene epoxidase inhibitor. FR194738 inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM.
    FR194738 free base (Standard)

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