4 Results for "

IP receptor agonist-1

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "IP receptor agonist-1" in MCE Product Catalog:

Cat. No.: HY-175986
CAS No.: 3029113-61-6
Research Areas:  

Inflammation/Immunology

IP receptor agonist 1 (compound 6c-14S) is an orally active I prostanoid receptor agonist, with an IC50 of 0.15 μM for inhibiting platelet aggregation induced by ADP (HY-W010918,300 μM) in rabbit platelet-rich plasma. IP receptor agonist 1 can be used for study of Pulmonary arterial hypertension .
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Cat. No.: HY-189067
IP/EP4 receptor agonist-1 is a PGI2 analog and also an IP/EP4 receptor agonist. IP/EP4 receptor agonist-1 inhibits PAR-mediated integrin αIIbβ3 activation, P-selectin exposure, platelet aggregation and thrombus formation. IP/EP4 receptor agonist-1 can be used in research related to pulmonary hypertension .
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Cat. No.: HY-79593S2
CAS No.: 1265295-20-2
Synonyms: ACT-333679-d7
MRE-269-d7 is deuterium labeled MRE-269 (HY-79593). MRE-269 is an active metabolite of selexipag, and acts as a selective IP receptor agonist .
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Cat. No.: HY-187539S
CAS No.: 3085716-86-2
Research Areas:  

Cardiovascular Disease

IPR agonist-1 is a prostaglandin-based IP receptor agonist. IPR agonist-1 binds to the IP receptor, forms hydrogen bonds with Tyr75-Ser168-Arg279, and undergoes π-π stacking with Tyr281, thereby triggering downstream signaling pathways. IPR agonist-1 inhibits ADP (Adenosine 5'-diphosphate) (HY-W010918)-induced platelet aggregation in rabbit platelet-rich plasma. IPR agonist-1 can be used in the research of pulmonary arterial hypertension .
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