1 Result for "

JAK2V617F-mediated

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JAK2V617F-mediated" in MCE Product Catalog:

Cat. No.: HY-50859
CAS No.: 1092939-16-6
Synonyms: INCB018424 sulfate
Target:  

JAK Autophagy

Research Areas:  

Cancer

Ruxolitinib sulfate (INCB018424 sulfate) is the first potent, selective JAK1/2 inhibitor to enter the clinic with IC50s of 3.3 nM/2.8 nM, and has > 130-fold selectivity for JAK1/2 versus JAK3.
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