21 Results for "

Jagged

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "Jagged" in MCE Product Catalog:

18
18 Publications Verification
Cat. No.: HY-P1846
CAS No.: 219127-21-6
Target:  

Notch

Research Areas:  

Cancer

Jagged-1 (188-204) is a fragment of the Jagged-1 (JAG-1) protein with Notch agonist activity. JAG-1 is a Notch ligand highly expressed in cultured and primary multiple myeloma (MM) cells. JAG-1 induces maturation of monocyte-derived human dendritic cells .
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18
18 Publications Verification
Cat. No.: HY-P1846A
Target:  

Notch

Research Areas:  

Cancer

Jagged-1 (188-204) TFA is a fragment of the Jagged-1 (JAG-1) protein with Notch agonist activity. JAG-1 is a Notch ligand highly expressed in cultured and primary multiple myeloma (MM) cells. JAG-1 induces maturation of monocyte-derived human dendritic cells .
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10
10 Cited Publications
Cat. No.: HY-N0711
CAS No.: 499-75-2
Synonyms: Cymophenol
Carvacrol is an orally active and blood-brain barrier-permeable monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations .
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2
2 Cited Publications
Cat. No.: HY-P1849A
Synonyms: scJag-1 TFA
Target:  

Notch

Research Areas:  

Cardiovascular Disease

JAG-1, scrambled (scJag-1) TFA is a scrambled sequence of JAG-1 (Jagged-1 protein). JAG-1, scrambled TFA has a random sequence of the amino acids that are the same as the active fragment. JAG-1, scrambled TFA is usually used as a negative control .
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1
1 Cited Publications
Cat. No.: HY-P71633
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Jag1; Protein Jagged-1; Jagged1; CD antigen CD339
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P73258
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AGS; Alagille syndrome; AWS; CD339; HJ1; JAG1; Jagged 1; JAGL1
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P70399
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: rHuJagged-1/JAG1, Fc; Protein Jagged-1 I; Jagged-1; JAGL1; HJ1; JAG1 and CD339
Species:  
Source:  
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Cat. No.: HY-N11709
CAS No.: 220114-28-3
Theasaponin E1 is an orally effective tea saponin. Theasaponin E1 inhibits the proliferation of cancer cells by activating apoptosis. Theasaponin E1 inhibits angiogenesis in ovarian cancer cells and HUVECs by reducing the expression of VEGF. Theasaponin E1 upregulates the phosphorylation level of ATM protein and the expression level of PTEN protein in cancer cells, decreases the phosphorylation levels of Akt, mTOR, p70S6K and 4E-BP1 proteins, downregulates the expression of HIF-1α and NF-κB, and reduces the protein expression of Notch ligands Dll4 and Jagged1. Theasaponin E1 exerts neuroprotective effects by inhibiting the activity of acetylcholinesterase, activating α-secretase and neprilysin, reducing the concentration of , and inhibiting the activities of β-secretase and γ-secretase. Theasaponin E1 exhibits toxic effects on cancer cells and quinone reductase-inducing activity, and inhibits tumor growth in vivo. Theasaponin E1 induces ferroptosis in Pomacea canaliculata by synergistically disrupting cholesterol homeostasis and sphingolipid metabolism. Theasaponin E1 possesses anti-biofilm activity against Candida albicans. Theasaponin E1 can be used in the research of ovarian cancer, obesity, Alzheimer's disease and fungal infections .
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Cat. No.: HY-P990206

Research Areas:  

Inflammation/Immunology

Anti-Mouse Jagged 2 Antibody (HMJ2-1) is an anti-mouse Jagged 2 IgG monoclonal antibody. Anti-Mouse Jagged 2 Antibody (HMJ2-1) regulates Treg/Th17 balance through IL-9. Anti-Mouse Jagged 2 Antibody (HMJ2-1) increases Jagged2-Notch signaling through activation of RBP-Jk. Anti-Mouse Jagged 2 Antibody (HMJ2-1) can be used for researches on inflammation conditions and xenotransplantation such as experimental autoimmune encephalomyelitis (EAE) .
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Cat. No.: HY-N0711R
CAS No.: 499-75-2
Synonyms: Cymophenol (Standard)
Carvacrol (Standard) is the analytical standard of Carvacrol. This product is intended for research and analytical applications. Carvacrol is an orally active and blood-brain barrier-permeable monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations .
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Cat. No.: HY-P1849
CAS No.: 402941-23-5
Synonyms: scJag-1
Target:  

Peptides

Research Areas:  

Cardiovascular Disease

JAG-1, scrambled (scJag-1) is a scrambled sequence of JAG-1 (Jagged-1 protein). JAG-1, scrambled has a random sequence of the amino acids that are the same as the active fragment. JAG-1, scrambled is usually used as a negative control .
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Cat. No.: HY-N9790
CAS No.: 79907-44-1
Procyanidin B2, 3,3'-di-O-gallate is an active constituent. Procyanidin B2, 3,3'-di-O-gallate can be isolated from grape seed extract (GSE) procyanidin mix. Procyanidin B2, 3,3' -di-o-gallate target cancer stem cells (CSCs) in prostate cancer (PCa). Procyanidin B2, 3,3'-di-O-gallate targets both unsorted and sorted CSCs at lower doses. Procyanidin B2, 3,3'-di-O-gallate strongly suppresses the constitutive as well as Jagged1 (Notch1 ligand)-induced activated Notch1 pathway .
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Cat. No.: HY-P83196
Synonyms: HJ2; JAG2; Jagged2; SER2; Syndactylism

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse

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Cat. No.: HY-P79094
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Protein Jagged-2; JAG2; Jagged2; hJ2
Species:  
Source:  
CHO
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Cat. No.: HY-P83346
Synonyms: JAG1; JAGL1; Protein Jagged-1; Jagged1; hJ1; CD339

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human

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Cat. No.: HY-P702515
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AGS; AHDMGC104644; Alagille syndrome; AWS; CD339 antigen; CD339; HJ1; JAG1; Jagged 1; Jagged1; JAGL1; protein Jagged-1
Species:  
Rat
Source:  
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Cat. No.: HY-P87717

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P80195
Synonyms: JAG1; AGS; AHD; AWS; HJ1; AGS1; JAGL1; AGS antibody; AHD antibody; AWS antibody; CD 339 antibody; CD339 antibody; CD339 antigen antibody; Headturner antibody; hJ1 antibody; Htu antibody; Jag 1 antibody; Jag1 antibody; JAG1_HUMAN antibody; Jagged 1 antibody; Jagged1 (Alagille syndrome) antibody; Jagged1 antibody; JAGL1 antibody; MGC104644 antibody; OTTHUMP00000030278 antibody; Protein Jagged-1 antibody; Ser 1 antibody; Ser1 antibody; Serrate 1 antibody; Slalom antibody

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P84438
Synonyms: JAG1; AGS; AHD; AWS; HJ1; AGS1; JAGL1; AGS antibody; AHD antibody; AWS antibody; CD 339 antibody; CD339 antibody; CD339 antigen antibody; Headturner antibody; hJ1 antibody; Htu antibody; Jag 1 antibody; Jag1 antibody; JAG1_HUMAN antibody; Jagged 1 antibody; Jagged1 (Alagille syndrome) antibody; Jagged1 antibody; JAGL1 antibody; MGC104644 antibody; OTTHUMP00000030278 antibody; Protein Jagged-1 antibody; Ser 1 antibody; Ser1 antibody; Serrate 1 antibody; Slalom antibody

Host:  

Mouse

Application:  

WB, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P84438A
Synonyms: JAG1; AGS; AHD; AWS; HJ1; AGS1; JAGL1; AGS antibody; AHD antibody; AWS antibody; CD 339 antibody; CD339 antibody; CD339 antigen antibody; Headturner antibody; hJ1 antibody; Htu antibody; Jag 1 antibody; Jag1 antibody; JAG1_HUMAN antibody; Jagged 1 antibody; Jagged1 (Alagille syndrome) antibody; Jagged1 antibody; JAGL1 antibody; MGC104644 antibody; OTTHUMP00000030278 antibody; Protein Jagged-1 antibody; Ser 1 antibody; Ser1 antibody; Serrate 1 antibody; Slalom antibody

Host:  

Mouse

Application:  

WB, FC, ELISA

Reactivity:  

Human

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