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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
KCNT1 gain-of-function mouse model
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "KCNT1 gain-of-function mouse model" in MCE Product Catalog:
Cat. No.: HY-138667
CAS No.: 2540502-26-7
Target:
Research Areas:
PRX-2904 is an orally effective and selective KNa1.1 (KCNT1/Slack/Slo2.2) inhibitor with an IC50 of 40 nM against human KNa1.1-WT. PRX-2904 reduces abnormal neuronal firing in KCNT1 gain-of-function (GoF) models by inhibiting KNa1.1 channel activity. PRX-2904 is useful for research on epilepsy associated with KCNT1 gain-of-function variants .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
