1 Result for "

KRAS mRNA G-quadruplex

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KRAS mRNA G-quadruplex" in MCE Product Catalog:

Referencia número: HY-189278
Target:  

Ras Apoptosis

Áreas de investigación:  

Cancer

KRAS-IN-64 is a KRAS inhibitor that inhibits KRAS translation by binding to and stabilizing the G-quadruplex in the 5'-UTR of KRAS mRNA, exhibits antiproliferative activity in KRAS-mutant cancer cells, and induces cell cycle arrest, non-apoptotic cell death, and PARP cleavage-mediated apoptosis (apoptosis). KRAS-IN-64 can be used for research on pancreatic cancer .
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