1 Result for "

KW 2581

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KW 2581" in MCE Product Catalog:

Cat. No.: HY-123868
CAS No.: 284045-56-3
Target:  

Steroid Sulfatase

Research Areas:  

Cancer

KW-2581 is a steroidal selective steroid sulfatase (STS) inhibitor with an IC50 of 4 nM. KW-2581 inhibits STS activity of ZR-75-1 cells with an IC50 of 13 nM. KW-2581 inhibits the E1S-stimulated growth of ZR-75-1 cells with an IC50 of 0.18 nM. KW-2581 inhibits sulfated-estrogen dependent growth of breast cancer cells both in vitro and in vivo. KW-2581 induced regression in E1S-induced tumor growth. KW-2581 can be studied in research on hormone receptors-positive breast cancer .
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