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L-Ala-D-Glu-m-DAP-D-Ala-D-Ala

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (1) MMP (2) Peptide-Drug Conjugates (PDCs) (1)
By Research Areas:	Cancer (2) Infection (1)

Inhibitors & Agonists

Peptides

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-P4905

*Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2*	MMP	Cancer
Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 is highly selective substrate for matrix metalloproteases 12 (MMP12) substrate with a kcat/Km value of 1.8510 ⁵ M ^-1s ^-1, and poor substrate of other MMPs with the exception of MMP13* (kcat/Km = 0.5310 ⁵ M ^-1s ^-1) and MMP9* (0.33*10 ⁵ M ^-1s ^-1) .

HY-P10775

BT1769	Peptide-Drug Conjugates (PDCs) MMP	Cancer
BT1769 is a MT1-MMP-targeted (K_D = 3.35 nM) Bicycle toxin conjugate. BT1769 can be used in the study for osteosarcoma. BT1769 consists of a novel bicyclic targeting peptide that selectively binds MT1-MMP; a cytotoxin MMAE; and an enzymatically cleavable dipeptide linker .

HY-P11330

L-Ala-D-Glu-m-DAP-D-Ala-D-Ala	Bacterial	Infection
L-Ala-D-Glu-m-DAP-D-Ala-D-Ala is a key structured peptide of peptidoglycan of gram-negative bacteria. Peptidoglycan is a network of L-Ala-D-Glu-m-DAP-D-Ala-D-Ala cross-linking the repeated units of N-acetylglucosamine (GlcNAc) and N-acetylmuramic acid (MurNAc). L-Ala-D-Glu-m-DAP-D-Ala-D-Ala can be used for bacterial metabolic labeling research .

Cat. No.	Nombre del producto	Target	Research Area

HY-P4905

*Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2*	MMP	Cancer
Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 is highly selective substrate for matrix metalloproteases 12 (MMP12) substrate with a kcat/Km value of 1.8510 ⁵ M ^-1s ^-1, and poor substrate of other MMPs with the exception of MMP13* (kcat/Km = 0.5310 ⁵ M ^-1s ^-1) and MMP9* (0.33*10 ⁵ M ^-1s ^-1) .

HY-P10775

BT1769	Peptide-Drug Conjugates (PDCs) MMP	Cancer
BT1769 is a MT1-MMP-targeted (K_D = 3.35 nM) Bicycle toxin conjugate. BT1769 can be used in the study for osteosarcoma. BT1769 consists of a novel bicyclic targeting peptide that selectively binds MT1-MMP; a cytotoxin MMAE; and an enzymatically cleavable dipeptide linker .

HY-P11330

L-Ala-D-Glu-m-DAP-D-Ala-D-Ala	Bacterial	Infection
L-Ala-D-Glu-m-DAP-D-Ala-D-Ala is a key structured peptide of peptidoglycan of gram-negative bacteria. Peptidoglycan is a network of L-Ala-D-Glu-m-DAP-D-Ala-D-Ala cross-linking the repeated units of N-acetylglucosamine (GlcNAc) and N-acetylmuramic acid (MurNAc). L-Ala-D-Glu-m-DAP-D-Ala-D-Ala can be used for bacterial metabolic labeling research .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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