BT1769
BT1769 is a MT1-MMP-targeted (KD = 3.35 nM) Bicycle toxin conjugate. BT1769 can be used in the study for osteosarcoma. BT1769 consists of a novel bicyclic targeting peptide that selectively binds MT1-MMP; a cytotoxin MMAE; and an enzymatically cleavable dipeptide linker.
For research use only. We do not sell to patients.
- Formula: C186H269N43O50S
- Molecular Weight:3939.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 3939.45
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Formula C186H269N43O50S
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Sequence
4-Pentynoic acid-βAla-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Ala-Dap(Me)-Ala-Asn-Glu-1Nal-Ala-Cys-Glu-Asp-Phe-Tyr-Asp-Tle-Dap(Me)-NH2(Dap(Me)&Cys bridged with TBMB)(Click with Azidoacetic acid-Val-Cit-PAB-MMAE)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)