2 Results for "

LSD1/EGFR-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "LSD1/EGFR-IN-1" in MCE Product Catalog:

Cat. No.: HY-168433
CAS No.: 336171-65-4
Research Areas:  

Cancer

LSD1/EGFR-IN-1 (compound L-1) is a potent inhibitor of LSD1, EGFR T790M/L858R and EGFR L858R/T790M/C797S, with IC50s of 6.24 and 2.06 and 5.01 μM, respectively. LSD1/EGFR-IN-1 plays an important role in cancer research [1].
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Cat. No.: HY-168968S
CAS No.: 3091379-82-4
ZJY-54 is an orally active dual-target inhibitor of EGFR/LSD1, with IC50 values of 3.8 nM and 0.6 μM, respectively. ZJY-54 can inhibit the proliferation of non-small cell lung cancer cells, induce the accumulation of H3K4me2 and H3K9me2, and inhibit the phosphorylation of the EGFR signaling pathway. ZJY-54 has anti-tumor activity [1].
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